BACKGROUND Patients with "refractory angina" (RA) unsuitable for coronary revascularization experience high levels of hospitalization and poor health-related quality of life. Randomized trials have shown spinal cord stimulation (SCS) to be a promising treatment for chronic stable angina and RA; however, none has compared SCS with usual care (UC). The aim of this pilot study was to address the k...

In their excellent and timely article ‘Patient and public involvement in patient-reported outcome measures: evolution not revolution,’ Sophie Staniszewska and colleagues make important points about the contribution of patients to the development of patient-reported outcomemeasures (PROMs), seeing ‘‘patients as research partners in the research process, not just as those individuals who are cons...

Patient health information is increasingly collected through multiple modalities, including electronic records, wearables, and connected devices. Computer-assisted history taking could provide an additional channel to collect highly relevant, comprehensive, accurate patient while reducing the burden on clinicians face-to-face consultation time. Considering restrictions time associated negative ...

Introduction: Telehealth (TH) is a potential solution to the increased incidence of chronic illness in an ageing population.The extent to which older people and users with chronic conditions accept and adhere to using assistive technologies is a potential barrier to mainstreaming the service. This study reports the development and validation of the Whole Systems Demonstrator (WSD) Service User ...

OBJECTIVES (1) To assess the acceptability of a gel solution of adrenaline (epinephrine) (1 in 2000) and cocaine (5%) for anaesthetising children's facial lacerations to the child, parent, and operator. (2) To assess the safety of the current protocol. SETTING The emergency unit of a large university hospital. METHODS All patients who were treated with topical adrenaline and cocaine (topAC)...

The quadrivalent human papillomavirus virus vaccine was recently licensed for use in males in the United States. This study reviews available published literature on acceptability among parents, health care providers, and young males. Among 23 published articles, half were conducted in the United States. The majority (87%) used quantitative survey methodology, and 13% used more explorative qual...

oral contraceptive pills have several side effects especially on the gastrointestinal tract and liver. absorption of low dose (ld) pills by the vaginal route avoids the first pass of the steroids through these tracts and probably has fewer side effects. this study was a cohort study for evaluation of side effects and acceptability of ld pills administered by the vaginal route. in a clinical tri...