Background: Many cardiovascular diseases may require lifelong anticoagulation therapy. Warfarin is the most prescribed medication in this regard, however, it has serious side effects. Recently the new issue regarding to warfarin dosing is considered in which some single nucleotide polymorphisms (SNPs) affecting cytochrome P450 system can impact on warfarin metabolism and dosing. Methods: 230 c...

background: pet/ct imaging using [18f]-fdg is utilized in clinical oncology for tumor detecting, staging and responding to therapy procedures. essential consideration must be taken for radiation staff due to high gamma radiation in pet/ct and cyclotron center. the aim of this study was to assess the staff exposure regarding whole body and organ dose and to evaluate environment dose in pet/ct an...

background: we have validated the monitor unit calculations from a commercially available treatment planning system (tps) for three intensity modulated radiotherapy (imrt) planning techniques for tangential breast irradiation by using ionization chamber measurements. materials and methods: treatment plans were generated for forty-two breast patients by a forward planned field in field technique...

paclitaxel is a highly effective anticancer agent. it is active against a broad range of cancers that are generally considered refractory to conventional chemotherapy. paclitaxel induces a peripheral neuropathy (pn) that is characterized by sensory symptoms such as numbness and paresthesia in a glove and stocking distribution. pn may be severe and dose limiting at initial doses above 275 mg/m2....

patients and methods we evaluated radiation exposure from initial and downstream testing in a prospectively collected, matched cohort evaluated for cp in the emergency department (ed) with either ccta compared with usual care over a median follow-up of 19.6 months. effective radiation dose was calculated using published conversion factors. results prospective, ecg-triggered acquisition using a ...

BACKGROUND Computed Tomography (CT) contributes up to 50% of the medical exposure to the United States population. Children are considered to be at higher risk of developing radiation-induced tumors due to the young age of exposure and increased tissue radiosensitivity. Organ dose estimation is essential for pediatric and adult patient cancer risk assessment. The objective of this study is to v...

the presence of radon in drinking water causes health risks associated with exposure from both inhalation and ingestion. since the studies show that faults near the water resources have a critical effect on the concentration of radon, kouhbanan active fault zone, to find water resources  with high radon concentration was chosen for the following investigation. water samples were taken from all ...

background: many radioactive compounds may be released into the environment and hence into the drinking water supplies due to the human activities. radionuclides can also enter the food chain if the contaminated water is used for drinking or irrigation purposes. objective: to estimate the annual effective dose of natural radioactive materials like 226ra and 40k in drinking water of wells in zan...

background: measurement of background radiation is very important from different points of view especially for human health. the aim of this survey was focused on determining the current background radiation in one of the highest altitude regions ( zagros mountains ), chaharmahal and bakhtiari province, in the south west of iran . materials and methods: the outdoors-environmental monitoring exp...

abstractbackground: 226 ra and 228 ra contents in foodstuffs of ramsar which is a coastal city in the northern part of iran were determined by gamma spectrometry. measurement results together with food consumption rates were used to estimate annual effective dose from  226 ra and 228 ra, due to consumption of food stuffs by inhabitants of ramsar city.materials and methods: a total of 33 samples...