When tissues are injured and blood vessels clot, the local environment becomes ischemic, meaning that there is a lack of adequate supply of oxygen and glucose delivered to the surrounding cells. The heat shock protein-90 (Hsp90) family proteins protect tissues from various environmental insults and participate in the repair of damaged tissue. Here, we report discovery of a new ischemia-responsi...

We assess the multi-planet systems discovered by the Kepler satellite in terms of current ideas about orbital migration and eccentricity damping due to planetdisk interactions. Our primary focus is on first-order mean motion resonances, which we investigate analytically to lowest order in eccentricity. Only a few percent of planet pairs are in close proximity to a resonance. However, predicted ...

The evolution of ecological idiosyncrasies in Madagascar has often been attributed to selective pressures stemming from extreme unpredictability in climate and resource availability compared to other tropical areas. With the exception of rainfall, few studies have investigated these assumptions. To assess the hypothesis that Madagascar's paucity of frugivores is due to unreliability in fruiting...

Sex chromosomes in Xowering plants evolved recently and many of them remain homomorphic, including those in papaya. We investigated the chromosomal location of papaya’s small male speciWc region of the hermaphrodite Y (Y) chromosome (MSY) and its genomic features. We conducted chromosome Xuorescence in situ hybridization mapping of Y-speciWc bacterial artiWcial chromosomes (BACs) and placed the...