Objective: Ecotourism is seen as a means to protect the natural environment through income generation, education, environmental preservation and sustainable involvement of local communities. Conservation (KA), Services (LA), Economic Development Infrastructure (PE), Control (PN) which are success factors in improving ecotourism performance (KE) can support tourism with quality experiences Theor...

Abstract Children with Group 3 medulloblastoma (MB) have a very poor long-term outcome and many do not survive beyond 5 years. Several drivers for MB been identified but none resulted in targeted therapy to date. LIN28B is stem cell factor upregulated associated worse survival. Here we investigate the role of pathway development. Pharmacologic inhibition feasible may provide unique opportunity ...

Abbreviations: UGH: Uveitis-Glaucoma-Hyphema; IOL: Intraocular Lens; ACIOL: Anterior Chamber Intraocular Lens; PCIOL: Posterior Chamber Intraocular Lens; GCA: Giant Cell Arteritis; NVI: Neovascularization of the Iris; YAG: Yttrium Aluminum Garnet; OD: Right Eye; OS: Left Eye; HbA1c: Hemoglobin A1C; PEE: Punctate Epithelial Erosion; IEI: Illinois Eye Institute; QD: 1 time a day; BID: 2 times a d...

Increasing confidence in using vitro and silico model-based data to aid the chemical risk assessment process is one of most significant challenges faced by regulatory authorities. A crucial concern taking full advantage scientifically valid physiologically-based kinetic (PBK) models. Nevertheless, assessors remain unwilling employ PBK models their daily work. Indeed, are not often included curr...

Oxaliplatin (OXA) resistance limits the efficiency of treatment for hepatocellular carcinoma (HCC). Studies have shown that PDZ-binding kinase (PBK) plays important roles in tumors. However, role PBK HCC is still a problem. In this study, we explored whether involved chemoresistance to OXA HCC. Expressions six cell lines and one human hepatocytes line were determined by real-time quantitative P...

Ochrobactrum anthropi, formerly known as CDC group Vd, is an oxidase-producing, gram-negative, obligately aerobic, non-lactose-fermenting bacillus of low virulence that occasionally causes human infections. It is highly resistant to all beta-lactams except imipenem. A clinical isolate, SLO74, and six reference strains were tested. MICs of penicillins, aztreonam, and most cephalosporins tested, ...

Sequestration of parasitized erythrocytes in the central nervous system microcirculation and increased cerebrospinal fluid lactate are prominent features of cerebral malaria (CM), suggesting that sequestration causes mechanical obstruction and ischemia. To examine the potential role of ischemia in the pathogenesis of CM, Plasmodium berghei ANKA (PbA) infection in CBA mice was compared to infect...

The present study aimed to screen for potential genes and subnetworks associated with pancreatic cancer (PC) using the gene expression profile. The expression profile GSE 16515 was downloaded from the Gene Expression Omnibus database, which included 36 PC tissue samples and 16 normal samples. Limma package in R language was used to screen differentially expressed genes (DEGs), which were groupe...