Forming polymeric core–sheath nanofibers is gaining prominence owing to their numerous potential applications, most notably in functional scenarios such as antiviral filtration, which attracting significant attention due the current COVID pandemic. This study has successfully designed and constructed a novel pressurized gyration vessel fabricate polymer nanofibers. Several water-soluble water-i...

Smart antibacterial materials capable of releasing antibiotic drugs upon exposure to external triggers are highly desired for various medical applications. Herein, the fabrication thermosensitive drug-loaded core−shell nanofibers using electrospinning technique combined with in situ UV photopolymerization is reported on. The method used shaping core structure comprising biodegradable polymer po...

The prevalence of osteoarthritis, a degenerative cartilage disease that causes joint surface erosion and loss mobility, emphasizes the need producing functional articular replacement. Tissue engineering has been focus recent research as possible strategy for regeneration repair. most widely used technique manufacture nanofibers is polymer electrospinning. Polylactic acid (PLA) polycaprolactone ...

The development of materials with hydrophobic properties has been widely explored in areas such as textiles, healthcare, sports, and personal protective equipment. Hydrophobic that arise from nanoparticles (nPs) directly promote other valuable properties, including self-cleaning capabilities, decreased bacterial growth, increased comfort. In this study, biodegradable poly(?-caprolactone) (PCL) ...

Introduction: The native inability of nervous system to regenerate, encourage researchers to consider neural tissue engineering as a potential treatment for spinal cord injuries. Considering the suitable characteristics of induced pluripotent stem cells (iPSCs) for tissue regeneration applications, in this study we investigated the adhesion, viability and proliferation of neural progenitors (de...

Dithranol is one of the oldest and most efficient drugs used in treatment psoriasis. One challenges with using dithranol its photostability, because it easily degrades when exposed to light. This study investigated potential coaxial core-sheath PCL/PVA nanofibers as a dual-functional system for enhancing photostability remote-controlled drug delivery psoriasis therapy. We have shown that titani...

This study describes development of a novel controlled drug release system for multiple drugs, it consisted of Chitosan nanoparticles/PCL composite electrospun nanofibers with core-sheath structures. Two model agents' rhodamine B and naproxen were successfully loaded in the core and sheath region respectively. The behavior of these two agents demonstrated a good controlled release and temporali...

A one-step, mild procedure based on coaxial electrospinning was developed for incorporation and controlled release of two model proteins, BSA and lysozyme, from biodegradable core-shell nanofibers with PCL as shell and protein-containing PEG as core. The thickness of the core and shell could be adjusted by the feed rate of the inner dope, which in turn affected the release profiles of the incor...