For several decades, computer’s memory has been volatile. High speed memories such as DRAM and SRAM have been used as main memory and cache memory respectively. Magnetic disks are used as the persistent secondary storage devices. The present DRAM based main memory has reached its energy limits. Due to the advent of nonvolatile memories like PCM, MRAM, RRAM, FeRAM and Flash, there is growing int...

Centrosomes consist of a pair of centrioles surrounded by an amorphous pericentriolar material (PCM). Proteins that contain a Pericentrin/AKAP450 centrosomal targeting (PACT) domain have been implicated in recruiting several proteins to the PCM. We show that the only PACT domain protein in Drosophila (the Drosophila pericentrin-like protein [D-PLP]) is associated with both the centrioles and th...

Phase change memory (PCM) as a newly developed storage medium has many attractive properties such as non-volatility, byte addressability, high density and low energy consumption. Thus, PCM can be used to build non-volatile main memory databases. However, PCM’s long write latency and high write energy bring challenges to PCM-based memory systems. In this paper, we propose an improvement over the...

Nowadays, many applications use spatial data for instance-location information, so storing spatial data is important. We suggest using R -Tree over PCM. Our objective is to design a PCM-sensitive R -Tree that can store spatial data as well as improve the endurance problem. Initially, we examine how R -Tree causes endurance problems in PCM, and we then optimize it for PCM. We propose doubling th...

We describe a new architecture for passive robots and haptic displays, which we call a programmable constraint machine (PCM). An n-dof PCM can, under computer control, exhibit constraints (smooth, impenetrable virtual surfaces of dimensionality < n), or it can allow free n-dof motion. At the heart of the PCM is a nonholonomic element, which is used as a continuously variable transmission (CVT)....

The dot immunobinding assay, a rapid, visually read test, was adapted for serodiagnosis and follow-up of paracoccidioidomycosis (PCM). Purified gp43 antigen was tested before and after sodium metaperiodate treatment. To evaluate the assay, it was tested with sera from PCM, histoplasmosis, Jorge Lobo's disease, aspergillosis, candidiasis, and cryptococcosis patients and healthy subjects. Native ...

As a promising nonvolatile memory technology, Phase Change Memory (PCM) has many advantages over traditional DRAM. Multilevel Cell PCM (MLC) has the benefit of increased memory capacity with low fabrication cost. Due to high per-cell write power and long write latency, MLC PCM requires careful power management to ensure write reliability. Unfortunately, existing power management schemes applied...

OBJECTIVES To elucidate the role of the pcm-tolCsm operon in the multidrug resistance of Stenotrophomonas maltophilia. METHODS The presence of the pcm-tolCsm operon was verified by RT-PCR. The phylogenetic relationship between the outer membrane proteins known to be involved in functional tripartite efflux in Escherichia coli, Pseudomonas aeruginosa and S. maltophilia was analysed. The contri...

In C. elegans, genome-wide screens have identified just five essential centriole-duplication factors: SPD-2, ZYG-1, SAS-5, SAS-6, and SAS-4 [1-8]. These proteins are widely believed to comprise a conserved core duplication module [3, 9-14]. In worm embryos, SPD-2 is the most upstream component of this module, and it is also essential for pericentriolar material (PCM) recruitment to the centriol...

We describe a new architecture for passive robots and haptic displays, which we call a programmable constraint machine (PCM). An n-dof PCM can, under computer control, exhibit constraints (smooth, impenetrable virtual surfaces of dimensionality < n), or it can allow free n-dof motion. At the heart of the PCM is a nonholonomic element, which is used as a continuously variable transmission (CVT)....