In murine cells expressing the PaeR7 endonuclease and methylase genes, the recognition sites (CTCGAG) of these enzymes can be methylated at the adenine residue by the PaeR7 methylase and at the internal cytosine by the mouse DNA methyltransferase. Using nonadecameric duplex deoxyoligonucleotide substrates, the specificity of the PaeR7 endonuclease for unmethylated, hemi-methylated, and fully me...

Anti-Müllerian hormone (AMH), a glycoprotein secreted from the fetal testis, is responsible for regression of the Müllerian duct in the male fetus. The aim of this study was to evaluate the usefulness of serum AMH as a biomarker for diagnosis of cryptorchidism in horses. Serum AMH concentrations were measured in intact stallions, hemi-castrated unilateral cryptorchid stallions, and geldings. In...

This study examined the ability of children with hemiplegia to perform motor imagery of their unaffected hand. Children (8-12 years) formed three groups--R-HEMI: right-sided hemiplegia, n = 21; L-HEMI: left-sided hemiplegia, n = 19; and Comparisons, n = 21. We expected no group differences on a simple imagined grasping task, but the hemiplegia groups to perform atypically on an imagined pointin...

Experimental studies are made on the hemi – cylindrically blunted fins for Mach 2.2 to examine the effect of dimples on shock wave / boundary layer interaction. Flow field details around hemi – cylindrically blunted fin has been captured using oil flow visualization, measurements of static and total pressures and the lambda shock has been captured by shadowgraphy. Configuration indicate nonstar...

Hydroxymethylcytosine has been shown to be involved in DNA demethylation and gene expression. Although methods to determine the position of hydroxymethylcytosine at single-base resolution have been reported, these methods involve some difficulties. Here, we report a simple method to analyze hydroxymethylcytosine in the CpG sequence utilizing the maintenance DNA methylation activity of DNMT1, wh...

The human NK cell receptor NKp80 stimulates cytotoxicity upon engagement of its genetically linked ligand AICL. However, the mechanisms underlying NKp80-mediated signaling are unknown. In this study, we dissected NKp80 signaling using the NK cell line NK92MI. We demonstrated that NKp80, but not NKp80 mutated at tyrosine 7 (NKp80/Y7F), is tyrosine phosphorylated. Accordingly, NKp80/Y7F, but not ...

The paper deals with the notion of quasi hemi-slant submersions from Lorentzian para Sasakian manifolds onto Riemannian manifolds. These are generalization and semi-slant submersions. In this paper, we also study geometry leaves distributions which involved in definition submersion. Further, obtain conditions for such to be integrable totally geodesic. Moreover, give characterization theorems p...