abstract background totally implantable central venous access devices (ports) have been available for over 10 years, but have not been achieved widespread use in pediatric oncology patients. ports facilitate the administration of chemotherapy in children with cancer. materials and methods in this study, early complications of implantable central venous access devices in children with different ...

Anaplastic lymphoma kinase-positive anaplastic large T-cell lymphoma is characterized by morphological variability. Morphological variants (non-common subtype) are associated with a poor outcome. They display abundant reactive bystander cells admixed with the lymphoma cells. So far, the difficulty in distinguishing lymphoma cells from bystander cells by visual inspection has prevented detailed ...

BACKGROUND Follicular lymphoma (FL) is the second most common adnexal lymphoma of the eye that almost all of them are reported in elderly patients. Primary FL of the eye has been reported in only two children. Pediatric FL appears to be biologically distinct from typical adult FL. In cases without other organ involvement excision alone with close monitoring is a treatment of choiceand the progn...

Introduction: Mature B-cell non-Hodgkin's lymphoma (MB-NHL) and T-cell lymphoblastic (T-LBL) account for ∼50% ∼20%, respectively, among the different pediatric NHL entities. Our understanding of genetic lesions profiling these patients may help to improve clinical management with lymphomas. The aim this study is analyze mutational status associations between features treatment outcomes in Chine...

Aberrant lymphoma epigenome is the result of a combinatorial contribution of changes in DNA methylation, histone modifications, and noncoding RNA (ncRNA) expression in lymphoma cells. All of the components of epigenome have been the focus of intense studies in various subtypes of lymphoma, which resulted in the deeper understanding of novel mechanisms of lymphomagenesis and revealed novel thera...

T-cell/Histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare pathology, uncommon in the children population, and few cases reported had wide range of clinical presentations, including advanced stage, extranodal involvement, bad prognosis. The authors report case 16-year-old male patient with no medical history, who presented single left axillary adenopathy. was diagnosed by immunohistochemi...