The influence of polyethyleneimine (PEI) on the electrochemical behavior of cyanide-free electrolytes with 5,5-dimethylhydantoin (DMH) as a complexing agent was investigated using cyclic voltammetry (CV), chronoamperometry, and cathodic polarization measurements. The gold electrodeposition displayed three-dimensional (3-D) progressive nucleation in both the absence and presence of PEI according...

Structurally well-defined ABA triblock copolymers with low molecular weight linear polyethylenimine (PEI) as A block and poly(ethylene glycol) (PEG) as B block have been prepared and used for gene delivery. PEI–PEG–PEI 2100–3400–2100 can effectively condense DNA, giving small-sized polyplexes (b100 nm) with reduced zeta-potentials (b10 mV). Initial experiments show that these polyplexes have a ...

Polyethylenimine (PEI) has attracted much attention as a DNA condenser, but its toxicity and non-specific targeting limit its potential. To overcome these limitations, Antheraea pernyi silk fibroin (ASF), a natural protein rich in arginyl-glycyl-aspartic acid (RGD) peptides that contains negative surface charges in a neutral aqueous solution, was used to coat PEI/DNA complexes to form ASF/PEI/D...

Persistent activation of signal transducer and activator of transcription 3 (STAT3) has been shown to impart several oncogenic features in many solid and blood tumors. In this study, we investigated the potential of nanoparticles based on polyethylenimine (PEI) modified with stearic acid (StA), to deliver siRNA for efficient STAT3 downregulation in B16 melanoma cells. The B16 cells were targete...

BACKGROUND The purpose of this study was to demonstrate the potential of magnetic poly(methyl methacrylate) (PMMA) core/polyethyleneimine (PEI) shell (mag-PEI) nanoparticles, which possess high saturation magnetization for gene delivery. By using mag-PEI nanoparticles as a gene carrier, this study focused on evaluation of transfection efficiency under magnetic induction. The potential role of t...

objective: dna vaccines have been widely used to develop immunity against various pathogens including parasites and viruses. the potential of dna vaccine to induce an effective immune response is related to the expression levels of the encoded protein in eukaryotic cells. therefore, optimization of plasmid dna delivery system is a major concern in protein expression in order to make an efficien...

Transarterial chemoembolization (TACE) plus percutaneous ethanol injection (PEI) have been used for patients with unresectable hepatocellular carcinoma (HCC). However, whether the combination therapy of TACE plus PEI is better than TACE or PEI alone in the treatment of HCC remains controversial. Thus, we conducted this meta-analysis to assess the efficacy of combined therapy for unresectable HC...

Pancreatic exocrine insufficiency (PEI) is a disease of diverse aetiology-e.g., majority of patients suffering from cystic fibrosis (CF) show PEI congenitally. Malnutrition and malabsorption of nutrients impair growth and nutritional status. As reduced fat digestion leads to a deficiency of fat-soluble vitamins the supplementation is standard, but absorption is a critical point in PEI-patients....

Two kinds of algal beads were prepared using a carrageenan-based alga (Chrondrus crispus) and an alginate-based alga (Laminara digitata) ionotropically gelled with K(I) and Ca(II), respectively: the process consists of biopolymer partial extraction followed by hydrogel formation. The beads were modified with branched polyethylenimine (bPEI) and glutaraldehyde (GA) using the impregnation method ...

Cell patterning has emerged as an elegant tool in developing cellular arrays, bioreactors, biosensors, and lab-on-chip devices and for use in engineering neotissue for repair or regeneration. In this study, micropatterned surfaces were created using the layer-by-layer lift-off (LbL-LO) method for analyzing canine chondrocytes response to patterned substrates. Five materials were chosen based on...