Anthocyanins are naturally occurring reddish pigments that abundant in fruits and vegetables. To investigate the mechanistic basis for the anti-tumor properties of anthocyanins, five aglycone (cyanidin, delphinidin, malvidin, pelargonidin, and peonidin) and four glycosylated (cyanidin-3-glucoside, malvidin-3-glucoside, pelargonidin-3-glucoside and peonidin-3-glucoside) anthocyanins were used to...

we developed an immunogen to stimulate multivalent immunity against hepatitis b surface antigen (hbsag) and hepatitis b core antigens (hbcag). immune responses specific for both hbsag and hbcag play an important role in controlling the infection. hbsag-specific antibodies mediate elimination of virions at an early stage of infection and prevent the spread of virus. the immunogen was constructed...

Two commercially available progestogen products for cattle, melengestrol acetate (MGA) and norgestomet (SMB), were evaluated for their ability to induce synchronized estrus in anovulatory ewes. Seasonally anestrous ewes (n = 232) were randomly assigned to one of seven treatments: 1) control (C); 2) MGA only (OMGA; .3 mg of MGA/d); 3) MGA+zeranol (RMGA; 2.5 mg of zeranol); 4) MGA+PG-600 (PMGA; 4...

Pioglitazone (PG) is one of thiazolidinediones used for the treatment of type II diabetes mellitus. Some reports of its hepatotoxicity exist, but the mechanism of its hepatotoxicity is not well known. In the present study, the protective effect of some ATP suppliers are investigated against mitochondrial toxicity of PG in isolated rat mitochondria. Mitochondrial viability was investigated by MT...