This study explored the application of 400-DS dissolution apparatus 7 for individual pellet dissolution methodology by a design of experiment approach and compared its capability with that of the USP dissolution apparatus 1 and 2 for differentiating the coat quality of sustained release pellets. Drug loaded pellets were prepared by extrusion-spheronization from powder blends comprising 50%, w/w...

A published mathematical model for growth of pellets of filamentous microorganisms has been tested by comparison of model predictions with experimental data on growth of Streptomyces coelicolor in liquid batch culture. The original model considered the classification of pellets into a range of size classes. Growth resulted in movement of pellets to classes of increasing size, while shear forces...

Plasma fueling with pellet injection, pacing of edge localized modes (ELMs) by small frequent pellets, and disruption mitigation with gas jets or injected pellets are some of the most important technological capabilities needed for successful operation of ITER. Tools are being developed at Oak Ridge National Laboratory that can be employed on ITER to provide the necessary core pellet fueling an...

Multiparticulate systems (pellets) of prasugrel hydrochloride were prepared by extrusion spheronization method using MCC (micro crystalline cellulose). Optimum spheronization time and method of drying were selected as the process parameters for the preparation of final batches. Various pellet properties were evaluated like size & shape analysis, flow properties, bulk & tapped density, friabilit...

ovis orientalis isphahanica has a restricted geographical range and is listed as vulnerable by iucn. however, there is not enough data on habitat associations of this taxon to be used as a base for conservation programmes. use of vegetation communities by isfahan mouflon in mouteh wildlife refuge was studied over a one-year period. habitat use was related to vegetation communities and habitat v...

We had previously demonstrated the participation of whole bone marrow cells from adult mice in the reconstitution of skin, including the epidermis and hair follicles. To get an insight into cell populations that give rise to the epithelial components of the reconstituted skin, we fractionated bone marrow cells derived from green fluorescent protein-transgenic mice by density gradient. Unexpecte...

Anti-inflammatory activity of the ethanolic extract of the leaves of Morus indica Linn. was studied in wistar rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (100 mg/kg, p.o.) inhibited carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction...

Rat liver ribosomes prepared from the rapidly sedimenting pellet of a liver homogenate or from the microsomal pellet by the treatment of these pellets with sodium deoxycholate in buffer are deficient in polyribosomes and contain primarily ribosome dimers. Dimer formation can be prevented and a good polyribosome pattern can be obtained from both these pellets provided treatment with sodium deoxy...

In this paper, we present a brief overview of Pellet: a complete OWL-DL reasoner with acceptable to very good performance, extensive iddleware, and a number of unique features. Pellet is the first sound and complete OWL-DL reasoner with extensive support for reasoning ith individuals (including nominal support and conjunctive query), user-defined datatypes, and debugging support for ontologies....