background: mucous membrane pemphigoid (mmp) is considered an autoimmune blistering disease that  predominantly affects mucous membranes. various treatments are available for controlling the diseases, but not all of them may respond. objective: in this review, the data on seventy patients with mmp who were under treatment of intravenous immunoglobulin (ivig) are categorized and then analyzed. t...

Pruritic urticarial papules and plaques of pregnancy (PUPPP) are among the most common pruritic dermatoses observed in pregnant women. PUPPP appears most frequently in the third trimester, in primigravidas, and in multiple gestation pregnancies. The eruption of changes occurs initially on the abdomen and extends over the thighs, legs, back, buttocks, arms, and breasts. Skin changes typical for ...

Objective: To determine the percentage occurrence, clinical features and the age distribution of pregnancy-related dermatoses in pregnant females who were referred from Maternity Hospital Makkah to dermatology department for management at King Abdul Aziz Hospital, Makkah, Saudi-Arabia. Methods: Patients who attended the dermatology clinic at King Abdul Aziz Hospital, Makkah were examined clinic...

Gestational pemphigoid (PG), a very rare pregnancy-associated bullous dermatosis, is associated with adverse pregnancy outcome (miscarriage, preterm delivery, foetal growth restriction). The major antigen in PG is collagen XVII (BP180). PG autoantibodies cross-react with collagen XVII in the skin and have been suggested to cause placental failure. On this basis, we evaluated clinical outcome an...

Book Reviews Jürgen Fuchs Oxidative Injury in Dermatopathology Springer, Heidelberg 1992 XΠ + 360 pp.; 122 fig.; 17 tables; DM 198.ISBN 3-540-54355-4 This book intends to be a comprehensive analysis of hundreds of publications dealing with free radicals and oxidative skin injury. The first chapters are a nice introduction to the biochemistry of oxidants and antioxidant systems. Links between fr...

Hormonal alterations contribute to the physiologic skin changes in pregnancy, which include hyperpigmentation and melasma, striae gravidarum and vascular phenomena, such as spiders, palmar erythema and varicosities. Hair, nails and sweat glands may also be affected. Dermatoses associated with pregnancy include herpes gestationis, impetigo herpetiformis, pruritic urticarial papules and plaques o...

Pemphigoid is a group of bullous diseases that have a diversified morphologic presentation and affects skin, oral mucosa and other mucosal membranes alone or in combination. In the literature, the condition has been subclassified into bullous pemphigoid and cicatricial pemphigoid (Mucous membrane pemphigoid) on the basis of primary organ of involvement. Oral pemphigoid, defined as cicatricial p...