نتایج جستجو برای: percent free psa density
تعداد نتایج: 997293 فیلتر نتایج به سال:
OBJECTIVES To evaluate PSA (Prostate-specific antigen) parameters in patients with lepromatous leprosy (LL). DESIGN In a retrospective study, 23 male patients with LL were evaluated. PSA parameters (serum total PSA (tPSA), free PSA (fPSA), free-to-total PSA ratio (f/tPSA), PSA Density (PSAD)) were assessed. PSA parameters were compared with a control group. RESULTS The mean tPSA, fPSA, f/tP...
PURPOSE An increasing serum prostate-specific antigen (PSA) level is the initial sign of recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation therapy (SRT) may eradicate locally recurrent cancer, but studies to distinguish local from systemic recurrence lack adequate sensitivity and specificity. We developed a nomogram to predict the probability of canc...
OBJECTIVE The influence of age on the performance of percent free prostate-specific antigen (%fPSA) in diagnosing prostate cancer (PCa) in East Asians is controversial. We tested the diagnostic performance of %fPSA in a multi-center biopsy cohort in China and identified the proper age-specific cutoff values to avoid unnecessary biopsies. METHODS Consecutive patients with a prostate-specific a...
Like other countries, Japan is recording a rapid increase in the incidence of prostate cancer. The use of serum PSA (prostate specific antigen) measurement as a blood marker for prostate cancer has become widespread. Higher levels of PSA are associated with a higher probability of a diagnosis of prostate cancer. Needle biopsies detect prostate cancer in 20–30% of cases with PSA levels of 4.1–10...
The landscape of prostate cancer has changed since the appearance of the first prostate-specific antigen (PSA) assay. PSA testing has gained rapid recognition since M. Kuriyama et al. (1 ) of Roswell Park first reported clinical studies using an enzyme immunoassay with anti-PSA rabbit antibody. Mikolajczyk and coworkers (2, 3) reported the presence of several free PSA isoforms and the potential...
More than a decade ago, several investigators found serum PSA levels in cancer-free men to correlate directly with age and prostatic volume. This provided the basis for the establishment of age-specific reference ranges for PSA constituting an attempt to improve sensitivity and specificity of serum PSA as a marker for prostate cancer. Differing age-specific reference ranges for PSA were establi...
OBJECTIVE To explore effects on serum lipids, pituitary-gonadal axis, prostate and bone turnover of the administration of the mixed oestrogen agonist/antagonist raloxifene in healthy elderly men. PARTICIPANTS Thirty healthy men aged 60-70 years randomly received raloxifene 120 mg/day (n=15) or placebo (n=15) for 3 months. MEASUREMENTS In this double-blind, placebo-controlled study, serum go...
BACKGROUND The sensitivity and specificity of a screening test are biased when disease status is not verified in all subjects and when the likelihood of confirmation depends on the test result itself. We assessed the screening characteristics of the prostate-specific antigen (PSA) measurement after correction for verification bias. METHODS Between 1995 and 2001, 6691 men underwent PSA-based s...
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