Perianal fistulas are a major problem in many patients with Crohn's disease. These are usually complex fistulas that adversely affect patients' quality of life, and their clinical management is difficult. Medical treatment sometimes achieves cessation of discharge and closure of the external opening; however, it is difficult to assess the status of the rest of the fistula tract. Magnetic resona...

Abstract Background Up to 30% of Crohn's Disease (CD) patients suffer from perianal fistula creating a high disease burden. Treating CD is challenging compared cryptoglandular fistula, which have significantly better wound healing response. Previous studies suggested epithelial mesenchymal transition as an inducer formation, markers were observed in tracts. However, most normal mucosa, thus dis...

Background: Anal fistulae, especially the complex and the high ones, are a challenge to treat even for an experienced surgeon. Hence, there is a need to preoperatively evaluate anal fistula to reduce the rate of recurrence. Objective: This study was embarked on to evaluate the natural course of anal fistula and its management. Goodsall’s rule, which predicts the course of fistulous tracts, was ...

PURPOSE The purpose of this paper is to present results of a single-center, nonrandomized, prospective study of the video-assisted anal fistula treatment (VAAFT). METHODS 68 consecutive patients with perianal fistulas were operated on using the VAAFT technique. 30 of the patients had simple fistulas, and 38 had complex fistulas. The mean follow-up time was 31 months. RESULTS The overall hea...

BACKGROUND Anorectal fistula represents an epithelized communication path of infectious origin between the rectum or anal canal and the perianal region. The association of endoscopic surgery with the minimally invasive approach led to the development of the video-assisted anal fistula treatment. AIM To describe the technique and initial experience with the technique video-assisted for anal fi...