OBJECTIVE The present study addresses the question, "Are plaque smooth muscles cells (SMCs) genetically distinct from medial SMCs as reflected by the ability to maintain a distinctive expression phenotype in vitro?" METHODS AND RESULTS Multiple cell strains were developed from carotid endarcterectomy specimens, and quadruplicate array hybridizations were completed for each sample. A new norma...

In this work, we propose a method based on Genetic algorithm hybridized with Pattern Search for joint estimation of Amplitude and Direction of Arrival, azimuth as well as elevation angles using L-type array. Four other schemes, i.e., the Genetic algorithm, Pattern Search, Simulated Annealing and Simulated Annealing hybridized with Pattern Search are also discussed and compared with Genetic algo...

Encryption algorithms are becoming more necessary to ensure data is securely transmitted over insecure communication channels. FOX is a recently developed algorithm and its structure is based on the already proven IDEA (International Data Encryption Algorithm) cipher. FOX is a symmetric (private key) block cipher. Its top-level structure uses the Lai-Massey scheme and the round functions used i...

Autoimmune thyroid disease (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), is one of the most common of the immune-mediated diseases. To further investigate the genetic determinants of AITD, we conducted an association study using a custom-made single-nucleotide polymorphism (SNP) array, the ImmunoChip. The SNP array contains all known and genotype-able SNPs across 186 ...

The set of synchronizing words a given n-state automaton forms regular language recognizable by an with \(2^n - n\) states. size recognizing for the is linked to computational problems related synchronization and length words. Hence, it natural investigate automata extremal this property, i.e., such that minimal deterministic has sync-maximal permutation groups have been introduced in [S. Hoffm...

This paper revisits the problem of sorting by reversals with tools developed in the context of detecting common intervals. Mixing the two approaches yields new definitions and algorithms for the reversal distance computations, that apply directly on the original permutation. Traditional constructions such as recasting the signed permutation as a positive permutation, or traversing the overlap g...

quency, the demodulated and sampled received signal can be modeled by, The problem of separating and estimating signals received by an array whose array manifold has an unknown structural form is usually referred to as the blind N X jÁ (t ) n k signal copy problem. In this paper we consider the x(t ) = a e +n(t ) = As(t ) +n(t ) (2) k n k k k blind signal copy problem for polynomial phase sign=...