This study investigated the effect of a lotic environment on morphological characteristics and energy metabolism in juvenile grass carp Ctenopharyngodon idella. The fish were stocked forced to swim for 12 h per day 4 weeks at three water current velocities 0.5, 2, body length s−1 (Bl s−1). control lentic with 0 Bl s−1. results showed that significantly increased weight, length, condition factor...

Submit Manuscript | http://medcraveonline.com Abbreviations: APOA1: Apolipoprotein A1; APOB: Apolipoprotein B; ATP: Adenosine Triphosphate; BMI: Body Mass Index; CRP: Cardio-Reactive Protein; DAG: Diacylglycerol or Diglyceride; FACoA: Fatty Acyl CoA; HbA1C: Hemoglobin A1c; HOMA-IR: Homeostatic Model Assessment of Insulin Resistance; HDL: High-Density Lipoprotein cholesterol; HSCRP: Highly Sensi...

Morphological and functional alterations of hepatic mitochondria have been documented in patients with alcoholic liver disease (ALD). Our recent study demonstrated that zinc level was decreased in whole liver and mitochondria by chronic alcohol feeding. The present study was undertaken to determine whether zinc deficiency mediates alcohol-induced mitochondrial electron transport chain (ETC) def...

Anthracycline anticancer drugs (e.g., doxorubicin or daunorubicin) can induce chronic cardiotoxicity and heart failure (HF), both of which are believed to be based on oxidative injury and mitochondrial damage. In this study, molecular and functional changes induced by chronic anthracycline treatment with progression into HF in post-treatment follow-up were analyzed with special emphasis on nucl...

OBJECTIVE Brown adipose tissue (BAT) thermogenesis is critical in maintaining body temperature. The dorsomedial hypothalamus (DMH) integrates cutaneous thermosensory signals and regulates adaptive thermogenesis. Here, we study the function and synaptic connectivity of input from DMH cholinergic neurons to sympathetic premotor neurons in the raphe pallidus (Rpa). METHODS In order to selectivel...

Skeletal muscle is capable of phenotypic adaptation to environmental factors, such as nutrient availability, by altering the balance between muscle catabolism and anabolism that in turn coordinates muscle growth. Small noncoding RNAs, known as microRNAs (miRNAs), repress the expression of target mRNAs, and many studies have demonstrated that miRNAs regulate the mRNAs of catabolic and anabolic g...