Current innovations in optical imaging, measurement techniques, and data analysis algorithms express the need for reliable testing and comparison methods. We present the design and characterization of silicone elastomer-based optical phantoms. Absorption is included by adding a green dye and scattering by adding TiO(2) or SiO(2) particles. Optical coherence tomography measurements demonstrate a...

Highly hydrophilic hollow polycaprolactone (PCL) microfibres were developed as building elements to create tissue-mimicking test objects (phantoms) for validation of diffusion magnetic resonance imaging (MRI). These microfibres were fabricated by the co-electrospinning of PCL-polysiloxane-based surfactant (PSi) mixture as shell and polyethylene oxide as core. The addition of PSi had a significa...

Software anthropomorphic breast phantoms have been used in virtual clinical trials for preclinical validation of breast imaging systems. Virtual trial quality depends largely on the realism of the simulated breast anatomy. Our phantom design has been focused on the simulation of large-scale and mesoscale anatomical structures, including the breast outline, skin, and matrix of Cooper’s ligaments...

In Diffusion Tensor Imaging (DTI), differently oriented fiber bundles inside one voxel are incorrectly modeled by a single tensor. High Angular Resolution Diffusion Imaging (HARDI) aims at using more complex models, such as a two-tensor model, for estimating two fiber bundles. We propose a new method for creating experimental phantom data of fiber crossings, by mixing the DWI-signals from high ...

BACKGROUND Magnetic resonance imaging (MRI) phantoms are routinely used for quality assurance in MRI centres; however their long term stability for verification of myocardial T1/ extracellular volume fraction (ECV) mapping has never been investigated. METHODS Nickel-chloride agarose gel phantoms were formulated in a reproducible laboratory procedure to mimic blood and myocardial T1 and T2 val...

introduction accurate estimation of the absorbed dose in radiosensitive organs, located away from the target volume during radiotherapy, is one of the main reasons for the development of reference phantoms. the international commission on radiological protection (icrp) reference phantoms can provide a more realistic view of the human anatomy in comparison with the previously used mathematical p...

objective(s): a novel iq-specttm method has become widely used in clinical studies. the present study compares the quality of myocardial perfusion images (mpi) acquired using the iq-specttm (iq-mode),conventional (180° apart: c-mode) and l-mode (90° apart: l-mode) systems. we assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. materials and me...

OBJECTIVE To evaluate our initial experience with a cone-beam breast computed tomography (BCT)-guided breast biopsy system for lesion retrieval in phantom studies for use with a cone-beam BCT imaging system. MATERIALS AND METHODS Under the Institutional Review Board approval, a phantom biopsy study was performed using a dedicated BCT-guided biopsy system. Fifteen biopsies were performed on ea...

OBJECTIVES To evaluate the accuracy of magnetic resonance imaging measurements of cartilage tissue-mimicking phantoms and to determine a combination of magnetic resonance imaging parameters to optimize accuracy while minimizing scan time. METHOD Edge dimensions from 4 rectangular agar phantoms ranging from 10.5 to 14.5 mm in length and 1.25 to 5.5 mm in width were independently measured by tw...

Reflectance imaging of biological tissues with visible and near-infrared light has the significant potential to provide a noninvasive and safe imaging modality for diagnosis of dysplastic and malignant lesions in the superficial tissue layers. The difficulty in the extraction of optical and structural parameters lies in the lack of efficient methods for accurate modeling of light scattering in ...