Departments of Medicine Community Health Sciences and of Physiology and Pharmacology, WHL Blood Pressure Screening Committee, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada; ISH Eastern Europe and Middle East Regional Advisory Group, American University of Beirut Medical Center, Beirut, Lebanon; Universit e du Qu ebec a Trois-Rivi eres, Quebec, Canada; Department of ...

BACKGROUND AND PURPOSE Subdural hemorrhage (SDH) is often associated with infants experiencing nonaccidental injury (NAI). A study of the appearance and natural evolution of these birth-related hemorrhages, particularly SDH, is important in the forensic evaluation of NAI. The purpose of this study was to determine the normal incidence, size, distribution, and natural history of SDH in asymptoma...

Resveratrol, a stilbenic compound deriving from the phenyalanine/polymalonate route, being stilbene synthase the last and key enzyme of this pathway, recently has become the focus of a number of studies in medicine and plant physiology. Increased demand for this molecule for nutraceutical, cosmetic and possibly pharmaceutic uses, makes its production a necessity. In this context, the use of bio...

Gene therapy offers significant advantages to the field of oncology with the addition of specifically and uniquely engineered mechanisms of halting malignant proliferation through cytotoxicity or reproductive arrest. To confer a true benefit to the therapeutic ratio (the relative toxicity to tumor compared to normal tissue) a vector or the transgene it carries must selectively affect or access ...

There is a large number of effective cytotoxic drugs whose side effect profile, efficacy, and long-term use in man are well understood and documented over decades of use in clinical routine e.g. in the treatment of recurrent glioblastoma multiforme (GBM) and the hormone-refractory prostate cancer (HRPC). Both cancers are insensitive against most chemotherapeutic interventions; they have low res...

The present work investigates the photocatalytic degradation efficiency of biorecalcitrant macrolide antibiotics in a circulating tubular photoreactor. As target pollutants, spiramycin (SPM) and tylosin (TYL) were considered in this study. The photoreactor leads to the use of an immobilized titanium dioxide on non-woven paper under artificial UV-lamp irradiation. Maximum removal efficiency was ...

Wissensmanagement gewinnt in der Industrie zunehmend an Bedeutung. Informationen sollen schichtübergreifend verfügbar sein, Mitarbeiter effizient für neue Tätigkeiten qualifiziert und Wissen über Generationen hinweg vermittelt werden. Der Beitrag zeigt hierzu Konzepte und konkrete Umsetzungen basierend auf mobilen Technologien auf, die im Rahmen des Förderprojekts Assist 4.0 entwickelt und eval...

Developing product software is getting increasing attention from both academics and practitioners. Organizations are recognizing the benefits and importance of developing a product for a market. Also, several software companies that develop customer-specific software have identified a need to change to developing and selling product software. Since few studies are available in this domain, it i...

Aktuell wird in Industrieunternehmen die zunehmende Digitalisierung, Vernetzung und IT-Durchdringung der Produktion unter dem Begriff Industrie 4.0 diskutiert. Aus der Umsetzung von Industrie 4.0 resultieren Änderungen, von denen die Prozessund Produktionsplanung (PPP) betroffen ist. Die Veränderungen werden anhand eines innovativen Use Case in der Motorenproduktion eines international agierend...