The embryonic chicken iris constricts to light ex vivo, but with characteristics atypical of visual phototransduction. The chick iris was most sensitive to short-wavelength light, demonstrating an action spectrum consistent with cryptochrome rather than with opsin pigments. Pupillary responses did not attenuate after saturating light exposure, but showed paradoxical potentiation. Iris photosens...

An 87-year-old man was referred to our photobiology unit in August 2015 for the diagnosis and treatment of eczematous lesions involving the sun-exposed areas (face, dorsal aspects of hands, and feet) that he had suffered from for >5 years. He had suffered from hypertension, and had experienced a cerebrovascular accident 10 years previously. Since then, triflusal (300mg twice daily) has been pre...

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Photodynamic therapy (PDT) utilizing Photofrin is proving to be effective for the treatment of early stage lung cancer. However, wider clinical applications of Photofrin as a photosensitizer for various cancers are hampered by potentially serious and prolonged skin photosensitivity. To prevent these side effects and reduce the hospitalization period, we recently gave reduced doses of Photofrin ...