نتایج جستجو برای: phthalimide derivatives
تعداد نتایج: 105202 فیلتر نتایج به سال:
[Structure: see text] The enantioselective hydrogenation of beta-phthalimide acrylates provides the corresponding chiral beta2-amino acids in excellent enantiomeric excess catalyzed by Rh-monophosphorus.
Thirteen years ago, without any pharmacological interests particularly, we have reported on preparations, electronic and crystal structures of a copper(II) complexes having 5,5-diphenylhydantoinate (phenytoinate; deprotonated phenytoin) and 2-phenylethylamine (phenethylamine) ligands (Figure 1) [1]. Before this paper, I (mainly supervised by the late Dr. Seiko Komorita at Osaka university, Japa...
An efficient N-heterocyclic carbene (NHC) catalyzed sulfenylation reaction of α,β-unsaturated aldehydes with N-(arylthio)phthalimide has been developed. A wide variety of α-thioenals can be obtained with good to excellent yields and excellent Z-configuration.
Despite the introduction of newly developed drugs such as lenalidomide and bortezomib, patients with multiple myeloma are still difficult to treat and have a poor prognosis. In order to find novel drugs that are effective for multiple myeloma, we tested the antitumor activity of 29 phthalimide derivatives against several multiple myeloma cell lines. Among these derivatives, 2-(2,6-diisopropylph...
Sixteen new phthalimide derivatives were synthesized and evaluated for their in vitro anti-microbial, anti-oxidant and anti-inflammatory activities. The cytotoxicity for all synthesized compounds was also determined in cancer cell lines and in normal human cells. None of the target derivatives had any cytotoxic activity. (ZE)-2-[4-(1-Hydrazono-ethyl) phenyl]isoindoline-1,3-dione (12) showed rem...
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