Many public health solutions to chronic diseases involve individual lifestyle choices: eating more healthfully, increasing physical activity, and quitting smoking. This approach neglects barriers in the community environment that make modifying unhealthy behaviors challenging. Addressing environmental barriers is an essential strategy to supporting behavioral changes. Changing community environ...

Detecting intracellular calcium signaling with fluorescent calcium indicator dyes is often coupled with microscopy techniques to follow the activation state of non-excitable cells, including lymphocytes. However, the analysis of global intracellular calcium responses both at the single-cell level and in large ensembles simultaneously has yet to be automated. Here, we present a new software pack...

The lattice conditional independence (LCI) model N(C)<) is defined to be the set of all normal distributions N(O, E) on IR I such that for every pair L, M E 1<, XL and xM are conditionally independent given xLnM (ct , [AP] (1993a)). Here C)< is a ring of subsets (hence a distributive lattice) of the finite index set I such that 0, IE ".K, while for K E 1<, XK is the coordinate projection of x E...

Rapid population growth, and human activities (such as agriculture, industry, transports,...) development have increased vulnerability risk for water resources. Due to the complexity of natural processes and the numerous interactions between hydro-systems and human pressures, water quality is difficult to be quantified. In this context, we present a knowledge discovery process applied to hydrol...

The present study aims to identify early cognitive impairment through the efficient use of therapies that can improve the quality of daily life and prevent disease progress. We propose a methodology based on the hypothesis that the dissociation between oral semantic expression and the physical expressions, facial gestures, or emotions transmitted in a person's tone of voice is a possible indica...

No studies to date have evaluated the relationship between exercise and microvascular function in youth with type 1 diabetes mellitus (T1DM). Twenty-nine complication free children and adolescents with T1DM were assessed for skin microvascular reactivity, aerobic fitness (VO2peak) and physical activity. VO2peak but not physical activity was significantly and independently associated with maxima...

OBJECTIVE Few studies have evaluated the determinants of perceived health in patients with chronic illness. The present study was designed to evaluate the role of biomedical, demographic, and psychosocial influences on global subjective health by means of a structural equation modeling approach. METHOD A conceptual model of perceived health was tested in a subsample of patients (N = 146) from...

PURPOSE This study examines the value of self-reported health (SRH) as an indicator of underlying health status in a developing country setting. DESIGN AND METHODS Logistic regression methods with adjustments for multistage sampling are used to examine the factors associated with SRH in 2,921 men and women aged 50 and older in rural Bangladesh. RESULTS SRH incorporates multiple dimensions o...