نتایج جستجو برای: pi ci integrator
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INTRODUCTION Modern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with virologic suppression. M ethods Cross-sectional data on 5152 (56.92% of the ...
BACKGROUND Liver diseases progress faster in human immunodeficiency virus (HIV)-hepatitis C virus (HCV)-coinfected persons than HIV-monoinfected persons. The aim of this study was to compare rates of liver fibrosis progression (measured by the aspartate-to-platelet ratio index [APRI]) among HIV-HCV-coinfected users of modern protease inhibitor (PI)- and nonnucleoside reverse transcriptase inhib...
BACKGROUND The unparalleled success of combination antiretroviral therapy (cART) is based on the combination of three drugs from two classes. There is insufficient evidence whether simplification to ritonavir boosted protease inhibitor (PI/r) monotherapy in virologically suppressed HIV-infected patients is effective and safe to reduce cART side effects and costs. METHODS We systematically sea...
BACKGROUND People with comorbid mental and physical illness (PI) experience worse health, inadequate care and increased mortality relative to those without mental illness (MI). The role of gender in this relationship is not fully understood. This study examined gender differences in onset of mental health service usage among people with physical illness (COPD, asthma, hypertension and type II d...
sensorless speed torque control of induction machines has been widely used in many industrial applications. the simple method of direct vector control can provide tacholess control as well as more complex approaches. in this method, the motor flux can be obtained by measuring voltage and current and integrating motor back electromotive force. the only required motor parameter is stator resistan...
Let denote a distance-regular graph with diameter D ≥ 3, valency k, and intersection numbers ai , bi , ci . Let X denote the vertex set of and fix x ∈ X . Let denote the vertex-subgraph of induced on the set of vertices in X adjacent x . Observe has k vertices and is regular with valency a1. Let η1 ≥ η2 ≥ · · · ≥ ηk denote the eigenvalues of and observe η1 = a1. Let denote the set of distinct s...
BACKGROUND Treatment of hepatitis C virus (HCV) infection with newer direct-acting antivirals is unrealistic in some countries because of the lack of availability. AIM Assess benefits and harms of boceprevir (BOC) and telaprevir (TLV) in treatment of genotype 1 HCV infection, and identifying subgroups with most benefit. MATERIAL AND METHODS Search from 2009-2013 in PubMed, EMBASE, and "gray...
As a common disorder that accounts for over 70% of all breast disease cases, mammary gland hyperplasia (MGH) causes a severe problem for the quality of patients' life, and confers an increased risk of breast carcinoma. However, the etiology and pathogenesis of MGH remain unclear, and the safety and efficacy of current western drug therapy for MGH still need to be improved. Therefore, a meta-ana...
BACKGROUND Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential. METHODS To study the impact of minor PI mutations on time to viral suppression and time to virological failur...
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