OBJECTIVES To evaluate pregnancy outcomes and its determinants in women with polycystic ovary syndrome (PCOS). METHODS Two-hundred and twenty pregnant PCOS and 594 healthy women were followed from early pregnancy. Incidences of gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), preterm birth, twinning, and fetal growth restriction (FGR) were determined. RESULTS The i...

Gallium nitrate is active against lymphoma and bladder cancer; however, little is understood about tumor resistance to this drug. Transferrin, the iron transport protein, increases gallium uptake by cells, whereas pyridoxal isonicotinoyl hydrazone (PIH), an iron chelator, transports iron into cells. Therefore, we examined whether these metal transporters would increase the cytotoxicity of galli...

CONTEXT Low cord blood leptin concentration is implicated as a risk factor for small for gestational age (SGA) babies. However, the association of strength, consistency, independence, and confounding factors of this affliction has not been systematically examined. OBJECTIVE To determine if there is a difference in cord blood leptin concentration between SGA and appropriate for gestational age...

The molecular mechanism that leads to pregnancy-induced hypertension (PIH), a pregnancy-specific syndrome, remains poorly understood. It has been suggested that microRNAs (miRNAs) may be potentially useful biomarkers for severe preeclampsia (PE), which is an important condition associated with PIH. The aim of the present study was to identify miR-204 by verifying differentially expressed serum ...

Background: Pregnancy Induced Hypertension (PIH) is a significant contributor to various pregnancy complications. Therefore, an effective way avoid possible fatal complications of the disease create awareness among pregnant women. Pregnant women who are aware danger signs will take responsibility for seeking medical attention if any arise. However, there lack study done at public hospitals in S...

Objective: To study the role of uterine artery notch on color Doppler ultrasound in prediction of PIH. Methods: This observational prospective longitudinal study was conducted in Department of Obstetrics and Gynaecology Mahatma Gandhi Medical College and Hospital, Jaipur. Study sample comprised of 100 antenatal patients with 20-28 weeks of gestation attending OPD of Department of Obstetrics and...

OBJECTIVE To test the hypothesis that elevated midpregnancy serum insulin (IRI) and C-peptide (CP) concentrations are associated with later development of pregnancy-induced hypertension (PIH), independent of prepregnancy obesity and midpregnancy blood pressure. RESEARCH DESIGN AND METHODS In this prospective study, a cohort of normotensive women, ages > or = years performed a 50-g glucose cha...

BACKGROUND Self-management is an important asset in helping older adults remain independent and in control for as long as possible. There is no reliable and valid measurement instrument to evaluate self-management behaviour of older adults. OBJECTIVE This study aims to design a measurement instrument, that is the Partners in Health scale for older adults (PIH-OA), to assess self-management kn...

OBJECTIVE To compare two transient models of synovitis-osteoarthritis (OA) in horses by characterizing biological changes in synovial fluid and joint tissue. METHOD Twelve skeletally mature mares were utilized in a block design. Synovitis was induced by an intra-articular injection of 100 ng recombinant equine interleukin 1 beta (reIL-1β) or 0.5 ng lipopolysaccharide (LPS) into a middle carpa...