نتایج جستجو برای: piperazines

تعداد نتایج: 199  

Journal: :Journal of Enzyme Inhibition and Medicinal Chemistry 2017

2014
Ebtehal S Al-Abdullah Hanadi H Asiri Siham Lahsasni Elsayed E Habib Tarek M Ibrahim Ali A El-Emam

The reaction of 5-(1-adamantyl)-4-phenyl-1,2,4-triazoline-3-thione (compound 5) with formaldehyde and 1-substituted piperazines yielded the corresponding N-Mannich bases 6a-f. The reaction of 5-(1-adamantyl)-4-methyl-1,2,4-triazoline-3-thione 8 with various 2-aminoethyl chloride yielded separable mixtures of the S-(2-aminoethyl) 9a-d and the N-(2-aminoethyl) 10a-d derivatives. The reaction of c...

2014
Ebtehal S. Al-Abdullah Hanaa M. Al-Tuwaijri Hanan M. Hassan Mogedda E. Haiba Elsayed E. Habib Ali A. El-Emam

The reaction of 5-(1-adamantyl)-4-ethyl or allyl-1,2,4-triazoline-3-thione with formaldehyde solution and various 1-substituted piperazines yielded the corresponding N-Mannich bases. The newly synthesized N-Mannich bases were tested for in vitro inhibitory activities against a panel of Gram-positive and Gram-negative bacteria and the yeast-like pathogenic fungus Candida albicans. Six compounds ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید