objective: there are some studies about the good effects of herbal medicine on blood glucose. this study was designed to evaluate the synergism effect of peganum harmala (p.harmala), quercus infectoria (q.i), vaccinium myrtillus (v.myrtillus), citrullos colocynthis (c.colocynthis), securigera securidaca (s.s) on blood glucosein type 2 diabetic patients. materials and methods: twenty four type 2...

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This article summarizes six lessons that can be learned from over a half century of scientific research on the placebo effect. These lessons are that the placebo response is not the placebo effect, it is meaningless to ask what the magnitude of the placebo effect is, it is easy to be fooled by regression artifacts, expectancy and conditioning are not conflicting processes that can be pitted aga...

Among studies with continuous outcomes in our systematic review comparing placebo effect sizes with treatment effect sizes we calculated mean differences between to estimate placebo effects, treatment effects, and the difference between placebo and treatment effects. In fact the standardized mean difference should have been used. There was no error in the calculations among studies with binary ...

AIM To evaluate techniques used to reduce the placebo effect in prior well-controlled, single or double-masked placebo-controlled glaucoma trials. METHODS This study was a retrospective, non-patient-based, observational review of phase I-III trials with a placebo arm for glaucoma medicines available after 1977. RESULTS This study included 20 articles with 20 placebo control arms consisting ...

The effect of placebo observed in schizophrenia clinical trials represents a growing problem that interferes with signal detection for treatments, increases costs of development, discourages investment in schizophrenia research and delays the introduction of new treatments. This paper seeks to clarify key issues related to this problem and identify potential solutions to them. Differences betwe...

BACKGROUND Insomnia is the most common sleep disorder. Treatment options are improved sleep hygiene, relaxation, cognitive behavioral therapy, and medications. Studies examining the effect of hypnotics on insomnia reported that placebo had a substantial beneficial effect. OBJECTIVES To evaluate whether placebo is an effective treatment for insomnia. METHODS We assessed 25 patients with inso...

Objective: There are some studies about the good effects of herbal medicine on blood glucose. This study was designed to evaluate the synergism effect of Peganum Harmala (P.harmala), Quercus Infectoria (Q.i), Vaccinium Myrtillus (V.myrtillus), Citrullos Colocynthis (C.colocynthis), Securigera Securidaca (S.s) on blood glucosein type 2 diabetic patients. Materials and Methods: Twenty four type ...

OBJECTIVE The message of the importance of a caring doctor-patient relationship is now like an old sermon which does not impact anyone's mind or action. Observing the healing practice of the old time physicians, who valued their attitudes and relationship with their patients more than the actual interventions, this paper reviews the literature on their main therapeutic device--the placebo effec...