نتایج جستجو برای: plant bioreactors
تعداد نتایج: 397823 فیلتر نتایج به سال:
S ingle-use bioprocessing equipment has come to thoroughly dominate precommercial biopharmaceutical production in only a decade. Yet even with this breakthrough, performance and cost pressures on biopharmaceutical facilities continue to grow. Demands for greater productivity, more efficiency, and lower costs are resulting in an unrelenting push for upstream improvements. Some people in the indu...
The aim of this study was to determine the reproducibility of small volume repeat sampling from replicate bioreactors with stabilized continuous-flow chicken cecal bacterial communities. Bacterial concentration and diversity were analyzed by phenotypic, biochemical and ribotype analysis. Significant differences in concentrations and variations in diversity were found in replicate bioreactors.
the mixing behavior of the gas-liquid phase in three loop bioreactors was investigated. a gas-induced external airlift loop bioreactor (ealb), a forced-liquid vertical tubular loop bioreactor (vtlb) and a forced-liquid horizontal tubular loop bioreactor (htlb) were used for mixing studies as well as biomass production from natural gas. the effect of design parameters, riser to downcomer cross s...
It is possible to use transgenic plants, as bioreactors, for the production of recombinant inexpensive chemicals and drug components. Transient gene expression is an appropriate alternative to stable transformation because it allows an inexpensive and rapid method for expression of recombinant proteins in plant tissues. In recent years, plant viral vectors have been increasingly developed as su...
Lactoferrin is a non-hematic iron-binding 80-kDa protein that exhibits antimicrobial activity. Higher plants function as “green bioreactors” for large-scale recombinant production. In this study, we transiently expressed human lactoferrin (rhLF) in Nicotiana benthamiana at yield of approximately 40 µg g−1 fresh mass (gFM) using the Tsukuba system. Additionally, expression level rhLF increased w...
BACKGROUND Single-use rocking-motion-type bag bioreactors provide advantages compared to standard stirred tank bioreactors by decreased contamination risks, reduction of cleaning and sterilization time, lower investment costs, and simple and cheaper validation. Currently, they are widely used for cell cultures although their use for small and medium scale production of recombinant proteins with...
Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article presents an overview of the engineering cha...
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