Vision begins when photons are captured by rhodopsin molecules in photoreceptor cells in the back of the retina. Activation of rhodopsin instigates a cascade of biochemical reactions, which eventually results in reduction of the steady (dark) current across the photoreceptor plasma membrane. This is the photoreceptor response, the signal that propagates to the brain enabling vision. Employing a...

The modelling of biochemical networks becomes delicate if kinetic parameters are varying, uncertain or unknown. Facing this situation, we quantify uncertain knowledge or beliefs about parameters by probability distributions. We show how parameter distributions can be used to infer probabilistic statements about dynamic network properties, such as steady-state fluxes and concentrations, signal c...

The current study was done to investigate the preclinical safety and toxicology of Althaea officinalis extract as naturopathic medicine in common carp (Cyprinus carpio). Specimens were treated with 0 (control), 2.5, 5 and 10 g of marshmallow extract for 45 days. Plasma biochemical parameters were measured after 15 and 45 days. Total protein, albumin and globulin levels (p<0.05) &nbsp;were signi...

Artificial fertilizers and mainly organophosphate herbicide are used by farmers to enhance their crop and control pests. In order to investigate the effects of Pretilachlore, fingerlings of caspian roach were exposed to a range of concentrations of toxin close to those of estuary for 96 h. Due to movement of these fingerlings in a gradient of salinity from freshwater to brackishwater some physi...