Cholesterol and its oxygenated metabolites, including oxysterols, are intensively investigated as potential players in the pathophysiology of brain disorders. Altered oxysterol levels have been described patients with numerous neuropsychiatric Recent studies shown that Bipolar disorder (BD) is associated disruption cholesterol metabolism. The present study was aimed at investigating profile oxy...

Psychotic patients treated with identical doses of antipsychotic drugs have been shown to have great interindividual differences in their steady state plasma concentration. Therefore, monitoring treatment by dosage adjustment alone is of little value. If antipsychotic blood levels can be related to clinical response then their routine measurement may well result in well defined guidelines to in...

objective: the results of the previous studies on the correlation between plasma levels of homocysteine (hcy) and ischemic stroke have been controversial. the aim of the present study is to investigate this correlation meticulously observing risk factors for the ischemic stroke as well as factors affecting the plasma levels of hcy. method: a case-control study was conducted between 2005-2006 wi...