INTRODUCTION Fibrillary glomerulonephritis (FibGN) is characterized by extracellular deposition of Congo red-negative microfibrils within the glomerular mesangium and leads to gross proteinuria or nephrotic syndrome. After diagnosis of FibGN, end-stage renal disease occurs within four years in 50% of patients. CASE PRESENTATION A 36-year-old Caucasian woman with proteinuria and intermittent n...

A patient with Waldenström's macroglobulinaemia presented with visual reduction in both eyes. The funduscopic and angiographic demonstrations of venous engorgement ('string of sausages'), retinal haemorrhages at all levels, retinal and disc oedema, and serous detachment of the maculas were consistent with this diagnosis. The cryoprecipitation of the immunoglobulin at a temperature slightly belo...

Autoimmune hemolytic anemia is a picture of hemolysis which is caused by autoantibodies against red blood cell surface antigens. It is classified as primary, secondary or warm and cold autoimmune hemolytic anemia according to the temperature at which antibodies react. It is usually an acute and self-limiting condition. Here, we present a three-year-old male patient who presented with malaise, p...

PATIENT Female, 10 FINAL DIAGNOSIS: Polyangiitis Symptoms: Intracranial hemorrhage • swelling • oliguria MEDICATION Cyclophosphamide • prednisolone Clinical Procedure: Plasmapheresis Specialty: Paediatric nephrology • nephrology • paediatrics. OBJECTIVE Rare disease. BACKGROUND MPO ANCA-associated vasculitis is very rare in children. Renal disease is almost universally present but lung an...

An imbalance of angiogenic and antiangiogenic placental factors such as endoglin and soluble fms-like tyrosine kinase 1 has been implicated in the pathophysiology of preeclampsia. Extraction of these substances by plasmapheresis might be a therapeutical approach in cases of severe early-onset preeclampsia. Case Report. A 21-year-old primigravida with antiphospholipid syndrome developed early-on...

The case of a 34 year old woman with systemic lupus erythematosus with a history of three previous recurrent abortions and lupus anticoagulant and anticardiolipin antibodies is reported. Immunoadsorbent plasmapheresis with a dextran sulphate column was used to remove lupus anticoagulant, anticardiolipin antibodies, and antibodies to DNA during her fourth pregnancy in combination with low doses ...

To the Editor: Thrombosis associated with severe thrombocytopenia is an infrequent, but life-threatening side effect of heparin therapy, which can involve any venous or arterial territory including the cerebral circulation. The treatment of this serious complication has not been satisfactorily resolved. Recently, Becker and Miller reviewed heparin-induced thrombocytopenia with thromboembolism a...

Mortality among patients suffering from meningococcal septicaemia has reached nearly 50% in parts of northern Norway despite intensive care. The activation of complement and blood cells by endotoxin is assumed to be the cause of most of the associated pathophysiological changes. Consequently, it would seem logical to remove such constituents either by combined plasmapheresis and leucapheresis o...

.AMONG the many complications suffered by patients with Waldenstriim’s macroglobulinemia are those related to increased blood viscosity.16 These include vascular stasis, retinopathy, and a bleeding disorder due to acquired functional thrombopathy.4 T h e latter is considered due to coating of platelets by macroglobulin, rendering them incapable of participating normally in the coagulation proce...

Objective: To compare computed tomographic (CT) appearance of the thymus with results from histologic examination of thymic tissue and clinical outcome in patients with myasthenia gravis who underwent thymectomy with or without plasmapheresis. Method and Materials: This study comprised of 47 patients, who were operated on in the period from January 2002 to December 2009 for myasthenia gravis. C...