While pleural effusion in multiple myeloma is relatively infrequent, myelomatous pleural effusion is extremely rare. We experienced a 61-year-old woman with IgD-lambda multiple myeloma and pleural effusion. The diagnosis was made originally by pleural biopsy, pleural fluid cytology and immunoelectropheresis of pleural fluid. Transient improvement of the pleural effusion was observed after admin...

BACKGROUND Transudative pleural effusions due to pleuroperitoneal communication occur in 1.6-10% of patients receiving peritoneal dialysis (PD) and usually have overtly elevated glucose concentrations. METHODS We report two cases of verified pleuroperitoneal communication with minimally elevated pleural fluid glucose levels. We reviewed the literature of all PD patients with pleuroperitoneal ...

BACKGROUND Carrageenin (CAR) injection into the pleural cavity causes local inflammation called carrageenin-induced pleurisy (CAR-IP). Inflammation onset is characterized by an activation of pro-inflammatory NFkappaB, RelA-p50, while inflammation resolution is characterized by an activation of an anti-inflammatory NFkappaB, p50-p50, that re-establishes homeostasis, an essential process for an o...

BACKGROUND Although the impact of therapeutic thoracentesis on lung function and blood gases has been evaluated in several studies, some physiological aspects of pleural fluid withdrawal remain unknown. The aim of the study was to assess the changes in pleural pressure amplitude (Pplampl) during the respiratory cycle and respiratory rate (RR) in patients undergoing pleural fluid withdrawal. M...

BACKGROUND Differentiation between exudative and transudative pleural effusions is the initial step in assessment of pleural effusion. The aim of this study was to determine whether high sensitivity C-reactive protein (hsCRP) and tumor necrosis factor α (TNFα) are diagnostic utilities for exudative pleural effusion. METHODS This experimental study assessed 79 patients with pleural effusion wh...

Tuberculous Pleural effusion is one of the most frequent causes of exudates in large series of pleural effusions in immunocompetent patients. The Aim of this study is to estimate enzyme Alkaline Phosphatase levels in serum and pleural fluids of HIV seronegative exudative Tuberculous Pleural fluids and their possible role in the diagnosis of tubercular pleural effusion. Serum and Pleural fluid s...

BACKGROUND The nonspecific clinical presentation and paucibacillary nature of tuberculous pleuritis remains a challenge for diagnosis. Diagnosis of tuberculous pleural effusion depends on the demonstration of the presence of tubercle bacilli in the sputum, pleural fluid, or pleural biopsy specimen, or demonstration of granuloma in pleura by histological examination. We examined the clinical uti...

Results: Increase Uric acid level was observed in pleural fluid of transudative pleural effusion than exudative pleural effusion. It was also observed that the level of uric acid was more in pleural fluid than serum and ratio (pleural fluid / serum) of uric acid was ≥ 1 in transudative conditions but in case of exudative condition the this ratio was < 1. The optimum cut-off level for P uric aci...

INTRODUCTION Pleural effusion is an abnormal accumulation of fluid in the Pleural space. e pleural space lies between the lung and chest wall and normally contains a very thin layer of fluid, which serves as a coupling system. Excess fluid results from the disruption of the equilibrium that exists across pleural membranes. Pleural effusion is an indicator of a pathologic process that may be of...

The penetration of cefoperazone and moxalactam into pleural fluid was studied in 11 patients after intravenous infusion of 2-g doses of these agents. Clearance of these agents from pleural fluid was studied in seven patients after instillation of 1-g doses into the pleural space. The concentrations in pleural fluid after intravenous infusion of 2-g doses reached a peak of 7 to 25 micrograms/ml ...