Introduction: The development of antioxidant cosmetic products based on natural added to nanotechnology is gaining more and prominence. However, some these actives are hydrophobic, which makes their placement in aqueous systems impossible. As a strategy deliver hydrophobic hydrophilic gels, nanoemulgels have been presented.
 Materials Methods: present study aimed prepare an nanoemulgel gua...

Mixed Pluronic micelles from very hydrophobic and very hydrophilic copolymers were selected to scrutinize the synergistic effect on the self-assembly process as well as the solubilization capacity of ibuprofen. The tendency of mixing behavior between parent copolymers was systematically examined from two perspectives: different block chain lengths at same hydrophilicity (L92 + F108, +F98, +F88,...

WATER-IN-OIL MICROEMULSIONS: COUNTERION EFFECTS IN AOT SYSTEMS AND NEW FLUOROCARBON-BASED MICROEMULSION GELS FEBRUARY 2010 XIAOMING PAN, B.S., TSINGHUA UNIVERSITY Ph.D., UNIVERSITY OF MASSACHUSETTS AMHERST Directed by: Professor Surita R. Bhatia Microemulsions have important applications in various industries, including enhanced oil recovery, reactions, separations, drug delivery, cosmetics and...

a multiple-unit oral floating system was prepared using the emulsification-solvent diffusion method to prolong the gastric emptying time of theophylline. for this purpose, theophylline, ethyl cellulose and dibutyl phthalate were dissolved in an ethanol/dichloromethane mixture, added to 0.1 m hcl containing nacl (20%) or saturated theophylline and/or different concentrations of polysorbate 80 an...

gamma-scintigraphy is applied extensively in the development and evaluation of pharmaceutical delivery systems, particularly for monitoring formulations in the gastrointestinal and respiratory tracts. the radiolabelling is generally achieved by the incorporation of an appropriate radionuclide such as technetium-99m or indium-111 into the formulation or by addition of a non-radioactive isotope s...

objective(s): nanoparticles (nps) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. the main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. methods: in this study, mesalamine loaded chitosan nanoparticles were pr...

The chitosan-pluronic nanoparticles have been prepared by an ionic gelation (IG) method. Particle size analysis, Scanning electron microscopy (SEM), Zeta potential measurements, Fourier transform infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC) were used for nanoparticles characterization. The optimized tamoxifen loaded nanoparticles had a spherical shape with positive ...

Cervical cancer is a leading cause of death among women. The endocervical adenocarcinoma (ECA) represents an aggressive and metastatic type with no effective treatment options currently available. We evaluated the antitumoral anti-migratory effects hypericin (HYP) encapsulated on Pluronic F127 (F127/HYP) photodynamic therapy (PDT) against human cell line derived from invasive cervical (HeLa) co...