BACKGROUND Pulmonary infections caused by Pneumocystis jirovecii in immunocompromised host can be associated with cysts, pneumatoceles and air leaks that can progress to pneumomediastinum and pneumothoraxes. In such cases, it can be challenging to maintain adequate gas exchange by conventional mechanical ventilation and at the same time prevent further ventilator-induced lung injury. We report ...

Pneumocystis jirovecii pneumonia (PCP) is a life-threatening infection in hematology. Although occasionally reported, the role of interhuman transmission of P. jirovecii in PCP, compared to that of reactivation, remains an unresolved question; the recommendation to isolate PCP patients in the hematology ward are not well evidence-based. Following an unexpected increase in the number of febrile ...

background and objectives: with increasing rate of immunodeficiency diseases in the world, opportunistic micro-organism such as pneumocystis jirovecii ( p. jirovecii ) become more important. little information is available on prevalence of this life- threatening microorganism in iran. this study was designed to determine the colonization and the rate of active disease caused by p. jirovecii in ...

Pneumocystis jirovecii pneumonia (PJP) is an opportunistic infection affecting immunocompromised patients. Patients with acute myeloid leukemia (AML) are not considered at high risk of PJP, thus, prophylaxis recommended. Between 2010 and 2020 we retrospectively analyzed 251 AML We performed molecular diagnosis genotyping in 67 bronchoalveolar lavage samples. Eleven cases PJP were diagnosed, a p...

In this issue of the journal, Choukri et al [1] state that their study provides the first quantitative data on the spread of Pneumocystis jirovecii in exhaled air from infected patients. There are additional data in prior studies using air samples collected in rooms of patients diagnosed as having P. jirovecii showing that not only could the organisms be detected but also their types correlated...

Although it is well-established that children undergoing allogeneic stem cell transplants and treatment for leukemia should be offered prophylaxis against Pneumocystis jirovecii pneumonia, the risk for children with solid malignancies is less certain. This guideline has been developed with the aim of standardizing practice and optimizing the benefit versus risk of prophylactic medication in thi...