نتایج جستجو برای: poly β
تعداد نتایج: 256060 فیلتر نتایج به سال:
The design, synthesis and characterization of materials consisting of grafted poly(1 → 4-β-glucan) strands on silica is reported. The silanol-rich environment provided in these materials activates the glycosidic bond for hydrolysis under mild conditions.
The catalytic performance of thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) functionalized at the terminal position with randomly methylated β-cyclodextrin was demonstrated by the aqueous Rh-catalysed hydroformylation of higher olefins.
Marine microbes use alginate lyases to degrade and catabolize alginate, a major cell wall matrix polysaccharide of brown seaweeds. Microbes frequently contain multiple, apparently redundant alginate lyases, raising the question of whether these enzymes have complementary functions. We report here on the molecular cloning and functional characterization of three exo-type oligoalginate lyases (Oa...
PARP inhibitors (PARPi) are under clinical trial for combination cancer chemotherapy. In the presence of a PARPi, PARP-1 binds DNA strand breaks but cannot produce poly(ADP-ribose) polymers or undergo auto-poly(ADP-ribosyl)ation. DNA binding is persistent, hindering DNA repair. Methylated bases formed as a result of cellular exposure to DNA-methylating agents are repaired by DNA polymerase β (p...
Lysophosphatidic acid (LPA) is an important phospholipid mediator in inflammation and immunity. However, the mechanism of LPA regulation during inflammatory response is largely unknown. Autotaxin (ATX) is the key enzyme to produce extracellular LPA from lysophosphatidylcholine (LPC). In this study, we found that ATX was induced in monocytic THP-1 cells by TLR4 ligand lipopolysaccharide (LPS), T...
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