We demonstrate the specificity, regenerability, and excellent storage stability of short peptide-based systems for detection of immunoglobulin G (IgG). The bioactive component consisted of acetylated-HWRGWVA (Ac-HWRGWVA), a peptide with high IgG binding affinity, which was immobilized onto copolymer matrixes of poly(2-aminoethyl methacrylate hydrochloride-co-2-hydroxyethyl methacrylate) (poly(A...

The poly(ADP-ribose) polymerase (PARP) family of proteins use NAD(+) as their substrate to modify acceptor proteins with ADP-ribose modifications. The function of most PARPs under physiological conditions is unknown. Here, to better understand this protein family, we systematically analyse the cell cycle localization of each PARP and of poly(ADP-ribose), a product of PARP activity, then identif...

As a remarkable multifunctional material, ferroferric oxide (Fe3O4) exhibits considerable potential for applications in many fields, such as energy storage and conversion technologies. However, the poor electronic ionic conductivities of classical Fe3O4 restricts its application. To address this challenge, nanoparticles are combined with graphene (GO) via typical hydrothermal method, followed b...

OBJECTIVE Children who experience multiple victimizations (referred to in this paper as poly-victims) need to be identified because they are at particularly high risk of additional victimization and traumatic psychological effects. This paper compares alternative ways of identifying such children using questions from the Juvenile Victimization Questionnaire (JVQ). METHODS The JVQ was administ...

Detailed phase transition processes of poly(2-isopropyl-2-oxazoline) (PIPOZ)/poly(N-isopropylacrylamide) (PNIPAM) and PIPOZ/poly(N-vinylcaprolactam) (PVCL) mixtures in aqueous solution were investigated by DSC, temperature-variable (1)H-NMR, optical microscopy and FT-IR spectroscopy measurements accompanied with two-dimensional correlation spectroscopy (2Dcos) and perturbation correlation movin...

Composite membranes composed of highly conductive and selective layer-by-layer (LbL) films and electrospun fiber mats were fabricated and characterized for mechanical strength and electrochemical selectivity. The LbL component consists of a proton-conducting, methanol-blocking poly(diallyl dimethyl ammonium chloride)/sulfonated poly(2,6-dimethyl-1,4-phenylene oxide) (PDAC/sPPO) thin film. The e...

Amyotrophic lateral sclerosis (ALS) is associated with progressive degeneration of motor neurons. Several of the genes associated with this disease encode proteins involved in RNA processing, including fused-in-sarcoma/translocated-in-sarcoma (FUS/TLS). FUS is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family of proteins that bind thousands of pre-mRNAs and can regulate the...

The high temperature dependence of junctionless (JL) gate-all-around (GAA) poly-Si thin-film transistors (TFTs) with 2-nm-thick nanosheet channel is compared with that of JL planar TFTs. The variation of SS with temperature for JL GAA TFTs is close to the theoretical value (0.2 mV/dec/K), owing to the oxidation process to form a 2-nm-thick channel. The bandgap of 1.35 eV in JL GAA TFTs by fitti...