Silk protein-based materials are promising materials for the delivery of drugs and other active ingredients, due to their processability, biocompatibility, and biodegradability. The preparation of films composed of an engineered spider silk protein (eADF4(C16)) in combination with either a polyester (polycaprolactone) or a polyurethane (pellethane), and their physical properties are described. ...

regeneration and engineering of functional new tissues containing the neural network have great importance. progression of neural network into the dental tissue has a crucial role in dental tissue regeneration. in the present study polymer-ceramic blended scaffolds containing different weight percentages of carbon nanotube in poly caprolactone nanofiber matrix were fabricated. morphological, me...

Biodegradabilities of polymers and their composites in a controlled compost were described. Polycaprolactone (PCL) and poly(lactic acid) (PLA) were employed as biodegradable polymers. Biodegradabilities of PCL and PLA samples in a controlled compost were measured using a Microbial Oxidative Degradation Analyzer (MODA) according to ISO 14855-2. Sample preparation method for biodegradation test a...

Cell adhesion in three-dimensional scaffolds plays a key role in tissue development. However, stem cell behavior in electrospun scaffolds under perfusion is not fully understood. Thus, an investigation was made on the effect of flow rate and shear stress, adhesion time, and seeding density under direct perfusion in polycaprolactone electrospun scaffolds on human dental pulp stem cell detachment...

The properties of blends of polycaprolactone and starch (PCL/starch) and maleic anhydride (MAH)-grafted-polycaprolactone and starch (PCL-g-MAH/starch) were examined using Fourier transform infrared (FTIR) spectroscopy, H nuclear magnetic resonance (H NMR), differential scanning calorimetry (DSC), and mechanical testing. Mechanical and thermal properties of PCL became noticeably worse when it wa...

OBJECTIVE To analyze a new endodontic sealer material commercially known as Resilon and to describe in detail the experimental techniques employed that lead to the identification of the composite material. METHODS An extensive structural, thermal, and physical characterization was used to identify a new endodontic sealer material using the following techniques: Fourier transform infrared (FTI...

To extend the external control capability of drug release, iron oxide nanoparticles (NPs) encapsulated into polymeric microspheres were used as magnetic media to stimulate drug release using an alternating magnetic field. Chemically synthesized iron oxide NPs, maghemite or hematite, and the antibiotic ciprofloxacin were encapsulated together within polycaprolactone microspheres. The polycaprola...

Electrospun polycaprolactone (PCL) is able to support the adhesion and growth of h-osteoblasts and to delay their degradation rate to a greater extent with respect to other polyesters. The drawbacks linked to its employment in regenerative medicine arise from its hydrophobic nature and the lack of biochemical signals linked to it. This work reports on the attempt to add five different self-asse...