نتایج جستجو برای: polyether sulfone

تعداد نتایج: 3018  

Journal: :Cancer research 1997
G A Piazza D S Alberts L J Hixson N S Paranka H Li T Finn C Bogert J M Guillen K Brendel P H Gross G Sperl J Ritchie R W Burt L Ellsworth D J Ahnen R Pamukcu

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as sulindac, have cancer chemopreventive properties by a mechanism that has been suggested to involve cyclooxygenase inhibition and reduction of prostaglandin (PGE2) levels in the target tissue. To test this hypothesis, we studied the effect of dietary sulindac sulfone (500-2000 ppm), a metabolite of sulindac reported to lack cyclooxygenase in...

Journal: :The Biochemical journal 2011
Panchanan Maiti Roberto Piacentini Cristian Ripoli Claudio Grassi Gal Bitan

Aβ (amyloid β-peptide) is believed to cause AD (Alzheimer's disease). Aβ42 (Aβ comprising 42 amino acids) is substantially more neurotoxic than Aβ40 (Aβ comprising 40 amino acids), and this increased toxicity correlates with the existence of unique Aβ42 oligomers. Met³⁵ oxidation to sulfoxide or sulfone eliminates the differences in early oligomerization between Aβ40 and Aβ42. Met³⁵ oxidation t...

Journal: :Science Talks 2023

Loose nanofiltration (LNF) membranes can be used to treat textile wastewater if the meet stringent criteria on permeability, selectivity, and structural stability. In this work, a novel LNF membrane was developed by interfacial polymerization (IP) process between 1,3,5-tris(4-aminophenyl) benzene (TAPB) trimesoyl chloride (TMC). The structure of TAPB, which is symmetric non-planar triamine mono...

Journal: :Oncology reports 2006
Ramin Naim Ray C Chang Johannes Schultz Karl Hormann

Approximately 310,000 new cases of oral and pharynx cancer account for a major cause of neoplasm related morbidity and mortality world-wide. Unfortunately, the survival rate has not improved significantly in the last decade. The vast majority of head and neck cancer is squamous cell carcinoma. The major adhesion-proteins involved in the development and maintenance of all solid tissue are the Ca...

2014
Wael Ismail Ashraf M. El Nayal Ahmed R. Ramadan Nasser Abotalib

Despite the nutritional significance of sulfur, its influence on biosurfactants production has not been sufficiently studied. We investigated the expression of key biosurfactants production genes, rhlABC, in cultures of Pseudomonas sp. AK6U grown with inorganic or organic sulfur sources. AK6U grew with either inorganic sulfate (MgSO4), dibenzothiophene (DBT), or DBT-sulfone as a sole sulfur sou...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2012
Béatrice B Roques Marlène Z Lacroix Sylvie Puel Véronique Gayrard Nicole Picard-Hagen Isabelle Jouanin Elisabeth Perdu Pascal G Martin Catherine Viguié

In rats, the widely used insecticide fipronil increases the clearance of thyroxine (T(4)). This effect is associated with a high plasma concentration of fipronil sulfone, the fipronil main metabolite in several species including rats and humans. In sheep, following fipronil treatment, fipronil sulfone plasma concentration and thyroid disruption are much lower than in rats. We postulated that fi...

2001
Alfred Hassner Eugene Ghera Tamar Yechezkel Victoria Kleiman Thiagarajan Balasubramanian Daryl Ostercamp

Abstract: This lecture describes some of our studies of lithio derivatives of allyl sulfone carbanions which add α-regioselectively as well as anti diastereoselectively to Michael acceptor olefins. This can be ascribed to chelation in the Michael addition step. When the reaction leads to subsequent ring closure by using a bromoallyl sulfone, the latter acts as a methylenemethane synthon in a (3...

2016
Reiner Sebastian Sprick Baltasar Bonillo Rob Clowes Pierre Guiglion Nick J. Brownbill Benjamin J. Slater Frédéric Blanc Martijn A. Zwijnenburg Dave J. Adams Andrew I. Cooper

Linear poly(p-phenylene)s are modestly active UV photocatalysts for hydrogen production in the presence of a sacrificial electron donor. Introduction of planarized fluorene, carbazole, dibenzo[b,d]thiophene or dibenzo[b,d]thiophene sulfone units greatly enhances the H2 evolution rate. The most active dibenzo[b,d]thiophene sulfone co-polymer has a UV photocatalytic activity that rivals TiO2, but...

1998
Yuguo Du Robert J. Linhardt

A samarium-mediated Barbier reaction was performed to a€ord N-acetylneuraminic acid -Cglycosyl compounds (`` -C-glycosides'') in excellent yield. The neuraminic acid phenyl sulfone or 2-pyridyl sulfone derivatives reacted with ketones or aldehydes resulting in the instantaneous and stereospeci®c formation of Neu5Ac -C-glycosides. The phenyl and the 2-pyridyl sulfone derivatives were equally e€e...

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