Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and is associated with demyelination, neurodegeneration, and sensitivity to oxidative stress. In this work, we administered a nanodroplet formulation of pomegranate seed oil (PSO), denominated Nano-PSO, to mice induced for experimental autoimmune encephalomyelitis (EAE), an established model of MS. PSO compr...

The pomegranate seed oil (PSO), containing 17-α-estradiol, is one of the newly found phytosterols with synergistic health effects on estrogen related physiological conditions. Herein, PSO was assessed for its potential improving effects on bone characteristics in a rat model of menopausal syndrome. Three month old non-pregnant female Wistar rats (n = 30) were either sham-operated (SHAM) or ovar...

Seed oil blending is a novel approach that may enhance the antioxidant capacity. The study evaluated effect of sunflower (SO) with pomegranate seed (BPSO) from blanched seeds (95 °C/ 3 min) on oxidative stability and properties blends. SO unblanched (PSO) were used as controls. Blending BPSO PSO was assessed in following respective proportions: 90:10, 85:15, 80:20 (w/w) respect to total phenoli...

Top-down control analysis (TDCA) is a useful tool for quantifying constraints on metabolic pathways that might be overcome by biotechnological approaches. Previous studies on lipid accumulation in oilseed rape have suggested that diacylglycerol acyltransferase (DGAT), which catalyses the final step in seed oil biosynthesis, might be an effective target for enhancing seed oil content. Here, incr...

The pomegranate seeds of four Iranian commercial varieties  (Abanmahi (AB), Malas (MS), Pust Sefid (PS) and Shahvar (SH)) were evaluated in terms of some quality properties including protein, oil, dietary fiber, mineral contents and fatty acid composition. Physicochemical properties and antioxidant activity of pomegranate seed oils (PSOs) were also determined. The oil antioxidant activity was m...

This study was conducted to determine the antimicrobial activity of methanol and ethanol extracts of peels of pomegranate (Punica grana), orange (Citrus siensis) and lemon (Limona taris) against four foodborne pathogens (Listeria monocytogenes, Salmonella Typhimurium, Escherichia coli and methicillinresistant Staphylococcus aureus (MRSA) and a food spoilage bacterium (Pseudomonas fluorescens. I...