BACKGROUND Postoperative nausea and vomiting (PONV) is common; ondansetron is often used as prophylaxis or for breakthrough episodes. Vestipitant is a neurokinin 1 (NK-1) receptor antagonist that is effective for prophylaxis, but its efficacy for treating established PONV is unknown. This study was performed to evaluate the efficacy and safety of vestipitant, compared with ondansetron for the t...

postoperative nausea and vomiting (ponv) are one of the most common complications of anesthesia and without prophylactic intervention occurs by about one-third of patients under general anesthesia. the aim of this study was to compare the efficacy of ondansetron and metoclopramide in reducing ponv after laparoscopic cholecystectomy. in this study, 60 patients undergoing laparoscopic cholecystec...

background: nausea and vomiting are common complications of anesthesia and surgery. patients undergoing tympanoplasty are exposed to a higher risk of postoperative nausea vomiting (ponv). these complications may alter the results of reconstruction and anatomical alignments. numerous antiemetics have been studied to prevent and treat ponv in patients undergoing tympanoplasty. the aim of this stu...

BACKGROUND Postoperative nausea and vomiting (PONV) is a frequent complication in postoperative period. The aim of this article was to evaluate the effect of dexmedetomidine on PONV. METHOD RevMan 5.3 software was applied for performing statistic analysis. Twenty-four trials with 2046 patients were included. RESULTS The PONV of the dexmedetomidine group was significantly lower compared with...

The efficacy of ondansetron 4 mg and 8 mg was compared with placebo in the reduction of postoperative nausea, retching and vomiting (PONV) after middle ear surgery during general anaesthesia, in 75 patients, in a double-blind and randomized study. Both doses of ondansetron were predictors for a decrease in PONV and the number of doses of rescue antiemetic needed per patient (droperidol: from 0....

However, in our opinion he neglects the often occurring dangerously increasing cuff pressures and its consequences. Daniel Sessler is not discussing the ongoing numerous deaths caused by pipeline construction flaws. He argues that N2O is inexpensive. But is this true? Is it really inexpensive? At least a subanalysis of the ENIGMA 1 trial with >2000 patients included, found an increase in total ...

BACKGROUND AND OBJECTIVE despite the introduction of newer antiemetics in the prevention of postoperative nausea and vomiting (PONV), perphenazine is recommended in current guidelines, as the concept of multimodal management of PONV in high-risk patients requires more than two drugs to be combined. The aim of this quantitative systematic review was to assess the efficacy and safety of perphenaz...

Background Goreisan, a traditional Japanese Kampo medicine, may prevent postoperative nausea and vomiting (PONV). The purpose of this study was to evaluate the effect of Goreisan on PONV in a high-risk population in a randomized, double-blind, placebo-controlled manner. Findings Patients undergoing gynecological surgery were randomly allocated to the Goreisan and the control groups. General a...

Aim. Efficacy of granisetron and combination of granisetron and dexamethasone was evaluated for prevention of postoperative nausea and vomiting (PONV) in children undergoing elective strabismus surgery. Methods. A total of 136 children (1-15 years) were included. Children received either granisetron (40 mcg/kg) [group G] or combination of granisetron (40 mcg/kg) and dexamethasone (150 mcg/kg) [...

We compared the efficacy of inhaled isopropyl alcohol (IPA) with ondansetron for the control of postoperative nausea and vomiting (PONV) during a 24-hour period in 100 ASA class I-III women undergoing laparoscopic surgery. Nausea was measured postoperatively using a 0 to 10 verbal numeric rating scale (VNRS). The control group received ondansetron, 4 mg intravenously, and the experimental group...