Circulating tumor DNA (ctDNA) provides a promising noninvasive alternative to evaluate the efficacy of neoadjuvant chemotherapy (NCT) in breast cancer. Herein, we collected 63 tissue (aspiration biopsies and resected tissues) 206 blood samples (baseline, during (Chemo), after (Post-Chemo), operation (Post-Op), follow-up) from 32 patients, preformed targeted deep sequencing with customed 1021-ge...

introduction: the osteopetrosis is a common disease in man and animals which is characterized by calcium accumulation in bones. the purpose of this study is to eveluate the osteoblast ultrastructure in osteoptrotic op/op mouse. material and methods: in this study 5 op/op (experimental) and 5 control mouse were killed by overdose of choloroform. their femur bones were taken, decalcified by edta,...

Myringoplasty is often regarded as one of the easier operation in otology The principal failures in myringoplasty are reperforation of the eardrum, anterior blunting, lateralization or thickening of the graft, iatrogenic cholesteatomas, and eardrum retraction. The risk of post-operative perforation ranges between 7% and 27%. This is a brief review of the risk factor of post-op tympanic membrane...

PURPOSE Visual performance following toric intraocular lens implantation for cataract with moderate and severe astigmatism. SETTING Cataract services, Shroff Eye Centre, New Delhi, India. DESIGN Case series. METHOD This prospective study included 64 eyes of 40 patients with more than 1.50 dioptre (D) of pre-existing corneal astigmatism undergoing phacoemulsification with implantation of t...

B-type natriuretic peptide (BNP) response early after a tetralogy of Fallot's repair remains unclear. BNP was measured pre- and post-operatively (immediately, day 1) in 18 children undergoing corrective repair with concurrent echocardiography (pre-, post-op day 1) to assess right ventricular (RV) systolic dysfunction, restrictive physiology, wall motion and pulmonary regurgitation (PR). In the ...

BACKGROUND Various surgical methods are recommended for the therapy of chronic subdural hematoma (CSH). In this study, burr-hole continuous drainage (CD) and burr-hole one-time drainage (OTD) methods for the treatment of CSH are retrospectively compared. MATERIAL/METHODS Fifty patients with CSH referred to this clinic between July 1995 and December 2003 were selected for treatment. Twenty-one...

BACKGROUND The fractures of the distal radius are one of the most frequent cases in the pediatric population. The primary way of treating these fractures is conservative, with manual reduction and cast immobilisation. In patients where reduction and retention of the fracture cannot be achieved, a surgical approach is the treatment of choice. AIM To evaluate the benefits of using the minimally...

OBJECTIVE The objective of this study was to compare the incidence of post-operative depression in breast cancer patients who have undergone mastectomy with the incidence of post-operative depression in non-breast cancer participants (controls). METHODS Using data from the Korean Health Insurance Review and Assessment Service (HIRA), we selected 2,130 patients with breast cancer who have unde...

INTRODUCTION the transurethral resection of prostate TURP is the elective treatment for the small and medium adenomas. In this study they analyse the effectiveness, the results and the postoperative morbidity in the resection of the great adenomas. PATIENTS AND METHOD We study 340 patients with great adenomas and symptomatic infravesical obstruction that were operated with the low hydraulic p...

OBJECTIVE We aimed to investigate whether preoperative serum neutrophil gelatinase-associated lipocalin (sNGALpre-op) predicted postoperative acute kidney injury (AKI) during hospitalisation and 1-year cardiovascular and all-cause mortality following adult cardiac surgery. METHODS This study was a post hoc analysis of the Effect of Remote Ischemic Preconditioning on Clinical Outcomes in Patie...