In this paper, a posterior uveitis case was reported in a patient who was being followed and under treatment for Ankylosing Spondylitis. Toxoplasma antibodies were investigated and anti-toxoplasma IgG was positive. Systematic treatment (Sulfamethoxazole/Trimethoprim and Clindamycin) was started. Despite medical treatment, reduction in visual acuity and development of dense membranous condensati...

Anti-tumor necrosis factor-α (anti-TNF-α) agents represent a major breakthrough for the therapeutic management of different autoimmune conditions. Noninfectious uveitis may lead to various sight threatening complications. Hence, from extrapolation of the benefit observed in autoimmune systemic diseases, anti-TNF-α agents are widely used in the treatment of noninfectious uveitis. However, their ...

Three patients who developed bilateral anterior uveitis at the end of, or soon after, the apparently successful treatment of visceral leishmaniasis are described. The uveitis gave rise to secondary glaucoma in 2 of the patients, and in the third patient the eye lesions were associated with an episode of post kala-azar dermal leishmaniasis.

BACKGROUND Behçet's disease is a multisystem vasculitis of unknown origin. Standard treatment mainly comprises systemic immunosuppressive agents. Ocular involvement, mostly posterior uveitis with retinal vasculitis, leads to blindness in 20-50% of the involved eyes within 5 years. The efficacy of interferon alfa-2a was studied in patients with sight threatening posterior uveitis or retinal vasc...

Uveitis is an important cause of vision loss worldwide due to its sight-threatening complications, especially cystoid macular edema, as well as choroidal neovascularization, macular ischemia, cataract, and glaucoma. Systemic corticosteroids are the mainstay of therapy for noninfectious posterior uveitis; however, various systemic side effects can occur. Intravitreal medication achieves a therap...

Abbreviations: UGH: Uveitis-Glaucoma-Hyphema; IOL: Intraocular Lens; ACIOL: Anterior Chamber Intraocular Lens; PCIOL: Posterior Chamber Intraocular Lens; GCA: Giant Cell Arteritis; NVI: Neovascularization of the Iris; YAG: Yttrium Aluminum Garnet; OD: Right Eye; OS: Left Eye; HbA1c: Hemoglobin A1C; PEE: Punctate Epithelial Erosion; IEI: Illinois Eye Institute; QD: 1 time a day; BID: 2 times a d...

AIM To evaluate the safety and effectiveness of high dose intravenous steroid therapy (HDIST) in Behçet's disease patients with severe posterior segment uveitis attacks. METHODS Five patients with ocular Behçet's disease were treated with HDIST for severe posterior segment attacks. Two patients had vasculitis, one patient had papillitis, and the other two had retinitis; four patients also had...

OBJECTIVE This study aimed to describe the clinical characteristics of uveitis presenting de novo in the elderly. DESIGN The study design was a description of a retrospectively identified case series. PARTICIPANTS A population of 138 patients (209 eyes) with uveitis beginning after age 60 was analyzed. RESULTS Uveitis in the elderly accounted for 10.4% of the authors' uveitis population. ...

PurposeTo evaluate long-term efficacy and safety of extended treatment with adalimumab in patients noninfectious intermediate, posterior, or panuveitis.DesignOpen-label, multicenter, phase 3 extension study (VISUAL III).ParticipantsAdults who had completed a randomized, placebo-controlled parent trial I II) without failure (inactive uveitis) discontinued the after meeting criteria (active uveit...

PURPOSE Previous reports have identified noninfectious uveitis as a potential sequela following both intravitreal bevacizumab and ranibizumab injections. We present two unique cases of acute anterior uveitis following intravitreal bevacizumab that did not occur with subsequent ranibizumab injections. METHODS Case report. CONCLUSION These cases may reflect differences in the etiology of ante...