To test the hypothesis that endurance training is associated with a decreased lipemia after a high fat meal, 16 young men [22 to 34 years old, nine of whom were trained (T) and seven of whom were untrained (UT)] were recruited. T ran greater than 30 or biked greater than 100 miles a week, while UT had been sedentary for at least the preceding 3 months. Daily caloric intake and daily caloric exp...

BACKGROUND Postprandial hyperlipidemia impairs endothelial function and participates in the development of atherosclerosis. We investigated the postprandial effects of a dipeptidyl peptidase IV inhibitor, alogliptin, on endothelial dysfunction and the lipid profile. METHODS A randomized cross-over trial design in 10 healthy volunteers (8 males and 2 females, 35 ± 10 years) was performed. The ...

Chad M. Paton, Josef Brandauer, Edward P. Weiss, Michael D. Brown, F. M. Ivey, Stephen M. Roth, and James M. Hagberg. The hemostatic response to postprandial lipemia before and after exercise training. J Appl Physiol 101: 316–321, 2006. First published February 23, 2006; doi:10.1152/japplphysiol.01363.2005.—Chronic hypertriglyceridemia is thought to be atherogenic and is associated with an elev...

In the elderly, the rise in postprandial plasma triglyceride (TG) concentrations is increased, contributing to their increased risk of cardiovascular disease. We sought to determine the incorporation of ingested fat (whipping cream enriched with [1,1,1-(13)C]triolein) into plasma lipids during the postprandial period in six healthy elderly (67 ± 1 yr old) and six healthy young (23 ± 2 yr old) s...

Background and Objective: In this review, we have mainly examined the effect of age, smoking and hypertension on post prandial triglycerides, since an exaggerated postprandial accumulation of triglyceride promotes the development of atherosclerosis. This study was designed to test the hypothesis that smoking and hypertension are independently associated with postprandial hypertriglyceridemia an...