An eco-safe and facile multi-component domino reaction has been described for the synthesis of 1H-pyrazolo [1, 2-b] phthalazine-5, 10-dione derivatives. The products were obtained by a four-component condensation reaction between phthalimide, hydrazine monohydrate, aromatic aldehyde derivatives and malononitrile in the presence of a catalytic amount of copper (II) oxide (CuO) ...

Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) as a new nanoporous acid catalyst was used in the one-pot synthesis of polyhydroquinolines derivatives via the Hantzsch four component condensation reaction of aldehydes, b-ketoesters, dimedone and ammonium acetate under solvent free conditions with short reaction time in excellent yields. SBA-P...

Betaine hydrochloride (BHC), as an ionic salt was found to be an efficient and recyclable catalyst for the one-pot synthesis of 4-thiazolidinediones. The methodology of study was achieved by one-pot condensation of aromatic aldehydes, aromatic amine and mercaptoacetic acid in the presence of betaine hydrochloride (BHC) at reflux temperature in ethanol as solvent. The efficiency of Betaine hydro...

A facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot Knoevenagel condensation, Michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of Iron (III) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. Various aromatic aldehydes were uti...

Selectfluor [1-(chloro methyl) -4-flouro -1,4-di azonia bicyclo[2,2,2] octane bis (tetraflouro-borate)] catalyzed the preparation of quinoxaline and 2,3-dihydo pyrazine derivatives through one -pot condensation of 1,2-di amines with 1,2-di carbonyls in solvent and under solvent- free conditions. This catalyst is commercially available, inexpensive, reusable, stable to air and moisture, and rela...

in this work firstly fe2o3 nanoparticles were synthesized via a simple chemical method. properties of the product were examined by x-ray diffraction pattern (xrd), scanning electron microscope (sem) and fourier transform infrared (ft-ir) spectroscopy. vibrating sample magnetometer (vsm) shows nanoparticles exhibit ferromagnetic behavior. to continue some of the 2-naphthol condensed 1,3-oxazinon...

The Acylase "Amano" (AA)-catalyzed synthesis of valuable pyridin-2-ones via domino Knoevenagel condensation-Michael addition-intramolecular cyclization-oxidization reaction between aldehyde, cyanoacetamide and ethyl acetoacetate or cyclohexyl acetoacetate was developed in the sense of a one-pot strategy. Various aliphatic, aromatic and hetero-aromatic pyridin-2-ones could also be produced in th...

In this work firstly Fe2O3 nanoparticles were synthesized via a simple chemical method. Properties of the product were examined by X-ray diffraction pattern (XRD), Scanning electron microscope (SEM) and Fourier transform infrared (FT-IR) spectroscopy. Vibrating sample magnetometer (VSM) shows nanoparticles exhibit ferromagnetic behavior. To continue some of the 2-naphthol condensed 1,3-oxazinon...

regarding the green chemistry's goals, dicationic magnetic room temperature ionic liquid open up new avenue to introduce an amazing and efficient system for facilitating catalyst recovery in different organic reactions. ability of this dicationic magnetic room temperature ionic liquid catalyst in the one-pot three-components condensation reaction of benzil, aromatic aldehyde, and ammonium aceta...

1, 4-Diazabicyclo [2.2.2] octane (DABCO) was employed as a catalyst for one-pot synthesis of pyrano[2,3-d] pyrimidinone derivatives and MWNT- pyrimidinones from condensation reactions of aromatic aldehydes, malononitrile and thiobarbituric acid and MWNT-COCl . This method delivers the advantages of a simple method, environment friendly procedure, mild reaction conditions and high returns. The m...