Fernández-Gómez, L., A. Cortés-Avizanda, P. Tiago, F. Byrne, and J. Antonio Donázar. 2022. Food subsidies shape age structure in a top avian scavenger. Avian Conservation Ecology 17(1):23. https://doi.org/10.5751/ACE-02104-170123

Scavenger receptors bind and internalize modified low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Because the expression of scavenger receptors is not down-regulated by cholesterol, macrophages (Mphi) expressing scavenger receptors can internalize substantial quantities of cholesteryl ester from oxidized LDL and HDL, leading to foam cell formation. Mphi express several differe...

Nitric oxide (NO) regulates proliferation, differentiation and survival of neurons. Although NO is reported to involve in NGF-induced differentiation of PC12 cells, the role of NO has not been characterized in primary neuron cells. Therefore, we investigated the role of NO in neuronal differentiation of primary cortical neuron cells. Primary cortical neuron cells were prepared from rat embryos ...

the oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. tyrosol is an important antioxidant with a plenty ofbiological properties. there are many strategies such as clustering single drug units in orderto develop new drugs. the cluster effect can increase drug effects relative to single drug unit.calixtyrosol is the novel clu...

Superoxide (O2-.) was reduced by the addition of superoxide dismutase (SOD: O2-. scavenger) and catechins. In competitive reactions utilizing different concentrations of spin-trap agent, the IC50 values of each sample were changed. With regard to the Cu2+/H2O2 and Fe2+/H2O2 reaction systems, metal chelater, hydroxyl radical (.OH) scavenger and catechins eliminated the levels of .OH. For the Cu2...

Fully oxidized LDL (OxLDL) is believed to contribute to atherogenesis in part by virtue of uptake into macrophages via specific scavenger receptors. This phenomenon results in the formation of cholesterol-loaded foam cells, a major component of atherosclerotic lesions. The present study is directed at examining the effects of OxLDL and minimally oxidized LDL (MM-LDL) on scavenger receptor expre...