The present study is planned to investigate the effect of dandelion leaves water extract (DWE) on Schistosomiasis. Thirty-five adult male albino mice weighing 20-25 g were used and divided into two main groups, first group served as a normal control without infection (n=7); second was infected with S. mansoni (n=28). After 45 days post-infection four subgroups; subgroup treatment (IC) positive ...

Neurocysticercosis is being recognised more often now, because of advances in radio-imaging. No treatment was available for this disease till about a decade back. Praziquantel has provided new hope. From India, there are very few published reports on experience with this drug. Nine cases of neurocysticercosis are being presented, where praziquantel therapy has been tried. Five patients with tum...

We tested effects of praziquantel, an antischistosomal compound, on clinical and immunological parameters of chronic schistosomiasis japonica. Two Japanese patients, who had high antibody titers to Schistosoma japonicum antigens but no fecal schistosome eggs or no or mild symptoms complained, were treated with praziquantel. Within two years after treatment, anti-schistosome antibodies in sera f...

Schistosomiasis, a neglected tropical disease, is widespread chronic helminthiasis reported in 78 countries, predominantly those within sub-Saharan Africa, as well Latin America, Asia, and most recently, even Europe. Species of the causative blood fluke infect not only humans but also animals, hybrids between previously assumed human-specific animal-specific schistosomes are being increasingly ...

Praziquantel has been shown to be highly effective against all known species of Schistosoma infecting humans. Spherical nanoparticulate drug carriers made of poly(D,L-lactide-co-glycolide) acid with controlled size were designed. Praziquantel, a hydrophobic molecule, was entrapped into the nanoparticles with theoretical loading varying from 10 to 30% (w/w). This study investigates the effects o...

A case of neurocystercercosis resistant to treatment with repeated courses of albendazole and praziquantel (even in combination), leading to deterioration in clinical condition is described.

Studies relating to the treatment of human taeniasis in the Philippines using Atabrine, bithionol, and mebendazole are reviewed. Cure rates of 93.7% for Atabrine, 85%-100% for bithionol, and 84.62% for mebendazole are reported. Aside from these studies, recent experience in the treatment of Taenia saginata infections at the Department of Parasitology, College of Public Health, is also reported....