Introduction: Gall bladder is the most common surgically resected specimen as gallstones are one of major causes morbidity. There increasing incidence gall stones in India and more so North India. It can be due to changes life style such fat rich food sedentary style. Stones produce a wide variety mucosal ranging from inflammatory, metaplastic, dysplastic neoplastic lesions. Aim: This study was...

BACKGROUND The present study was undertaken to estimate and compare the levels of plasma total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL) and triglycerides in patients with oral precancerous lesions/conditions, oral cancer and normal subjects. MATERIALS AND METHODS The study comprised of 60 patients with oral precancero...

Clinical research of gastrointestinal precancerous lesions is a key point in primary preven‐ tion of gastrointestinal cancer. It’s a long time from superficial gastritis to atrophic gastri‐ tis and to the gastric carcinoma finally. So how to effectively carry on the long-term followup of the gastric precancerous lesions becomes a perplexing medical problem [8; 2; 3; 7]. The most accurate ways t...

Cervical cancers, a malignancy associated with oncogenic papilloma viruses, remain a major disease burden in the absence of effective implementation of preventive strategies. CD66(+) cells have previously been identified as a tumor-propagating subset in cervical cancers. We investigated the existence, differentiation state, and neoplastic potential of CD66(+) cells in a precancer cell line harb...

B3 lesions represent 3–10% of the histologically assessed lesions in mammography screening. They comprise different histopathological entities which provide benign histology, but are either known to show heterogeneity or to have an increased (albeit low) risk of associated malignancy, e.g. FEA, ADH, lobular neoplasia (LN), papillary lesions, radial scar, and phyllodes tumor. With regard to the ...

OBJECTIVE The identification of precancerous lesions is the basis of an early diagnosis, and of a treatment that allows, in the great part of cases, the preservation of organ functions. The aims of this study were: the evaluation of the less invasive treatment for precancerous lesion of the larynx to minimize the recurrences, the estimation of number of further operation required. METHODS A p...

Here we investigated CD44 protein expression and its polymorphisms in patients with chronic gastritis, precancerous gastric lesions, and gastric cancer; and we evaluated our result with the risk of CD44 protein expression and clinicopathological characteristics. Our results obtained by analyzing 162 gastric cancer patients, 125 chronic gastritis, and 165 precancerous gastric lesions from three ...

Endoscopic procedures are the gold standard in identifying, monitoring and treating gastrointestinal system lesions. The evaluation of benign, precancerous and malignant characteristics of these lesions requires good endoscopic inspection and precise pathological examination. Pyloric gland adenoma is a rare precancerous lesion defined in recent years and herein is reviewed in the present case a...

BACKGROUND Cyclin E is a cell cycle regulator which is critical for driving G1/S transition. Abnormal levels of cyclin E have been found in many cancers. However, the level changes of cyclin E in esophageal adenocarcinoma and its precancerous lesion have not been well studied. Here, we focus on the gene amplification and expression of cyclin E in these lesions, and aim to ascertain the relation...