Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

background: increased life expectancy and the growing phenomenon of aging can lead to increased burden of chronic diseases (cds) which adversely affects the overall health of elderly, their sexuality in particular. sexual life of aged population is overlooked in many of the societies. in the present narrative review, we aim to assess the impact of cds on sexual function of elderly people. mater...

introduction: motor skills play an important role during life span, and older adults need to learn or relearn these skills. the purpose of this study was to investigate how aging affects induction of improved movement performance by motor training. methods: serial reaction time test (srtt) was used to assess movement performance during 8 blocks of motor training. participants were tested in two...

Pituitary duplication is a rare malformation commonly associated with other major neural/craniofacial anomalies, easily shown by magnetic resonance imaging. The authors describe two girls with duplication of the pituitary gland and thickening of the hypothalamus, facial dysmorphism and precocious pubertal development. The pathogenesis of pituitary duplication and its relationship with precociou...

The rationale underlying the use of gonadotropin-releasing hormone analogues (GnRHa) to treat patients with central precocious puberty is reviewed. GnRHa are now considered the treatment of choice for patients with central precocious puberty, but the adult heights that these patients attain often fall short of what would be expected according to their genetic potential. This has led to investig...

Results The mean age at the start of treatment was 8.11 ± 0.70 years in group 1, 8.98 ± 0.38 years in group 2 and 9.46 ± 0.46 years in group 3, respectively. The mean predicted adult height (PAH) SDS at the start of treatment was -1.29 ± 1.16 in group 1, -1.14 ± 0.88 in group 2 and -1.87 ± 1.09 in group 3, respectively. Rate of growth during treatment with GnRHa combined with GH was higher sign...

To establish normative data and determine the value of fluorometric AutoDELFIA assays (Wallac Oy) in the investigation of precocious puberty, we determined serum levels of LH, FSH, testosterone, and estradiol under basal and GnRH-stimulated conditions in 277 normal subjects at various pubertal stages and in 77 patients with precocious puberty. A substantial overlap was observed in basal and GnR...

BACKGROUND Precocious puberty (PP) is defined as the appearance of secondary sex characteristic at an age <8 years in girls and <9 years in boys, or menarche <9 years in girls. OBJECTIVE To determine the etiologies and clinical characteristics of children presenting with PP. SUBJECTS AND METHOD The medical records of 307 children (292 girls, 15 boys) with PP (1995-2009) were reviewed. RES...

BACKGROUND Precocious puberty (PP) is defined as the appearance of symptoms of puberty in girls before 8 years of age and in boys under 9. Statistically, it occurs much more frequently in girls, while it is a rare pathology in boys. MATERIAL/METHODS Over the period of 10 years, between 1999 and 2009, 39 girls and 17 boys aged 18 months - 9 years were diagnosed with precocious puberty,, and tr...