Prognostication of newly diagnosed colorectal cancer (CRC) predominantly relies on stage as defined by the UICC-TNM and American Joint Committee on Cancer classifications. Tumour extent, lymph node status, tumour grade and the assessment of lymphatic and venous invasion are still the most important morphological prognostic factors. Evidence suggests that tumour budding and tumour border configu...

In their study, Fingelkurts et al (2006) demonstrated via EEG (electroencephalogram) that patients with depression have abnormal activity in the prefrontal lobe and the limbic system. Among the most suggestive changes are as follows: the presence of theta waves in the frontal lobe and the frequency increase of alpha and beta waves. Since the first discussions about poststroke depression (Robins...