The first cases of Yellow Hyaline Membrane Disease (YHMD) were seen in USA in the beginning of 1965, coinciding with the start of an active intensive care unit for premature infants and the era of prolonged survival of severe cases of respiratory distress syndrome in newborns. The lungs of newborns with YHMD can often be identified grossly by slight yellow discoloration. The yellow color is per...

PURPOSE To evaluate the feasibility of performing diffusion tensor tractography (DTT) to map and quantify the pyramidal white matter tracts of premature newborns. MATERIALS AND METHODS Fourteen diffusion tensor MRI (DTI) examinations of nine premature newborns were evaluated. DTT was performed to segment bilateral pyramidal tracts, using a fiber-tracking algorithm originating in the cerebral ...

Background: Premature birth and subsequent admission to the neonatal intensive care unit (NICU) may impair the neurodevelopment of neonates. The present study aimed to determine the effect of developmental care on neurodevelopmental outcomes of newborns.Methods: This quasi-experimental study was conducted on 105 premature neonates (in three groups of 35 newborns). The control group receiv...

OBJECTIVE To compare inflammatory mediators in the cord blood of premature newborn infants with premature rupture of membranes (PROM) and intact membranes. METHODS Eighty-nine premature neonates with gestational age of 27-34 weeks that delivered in Ghaem Hospital in Mashhad, Iran from June 2005 to March 2006 were enrolled in a prospective observational study, and their umbilical cord plasma w...

Background: Studies have shown that mothers of premature newborns have lower physical and psychological quality of life compared to mothers of healthy neonates. Therefore, applying a health promotion program for supporting them is necessary. Aim: To determine the effectiveness of a health promotion program on the quality of the life of mothers of premature newborns. Methods: In this quasi- expe...

Craniosynostosis is defined as the premature closure of the cranial sutures resulting in characteristic skull deformities. It is a rather frequent craniofacial malformation estimated to affect 1 in 2500 newborns [1]. There is a great variability in both phenotype and the underlying causes. Premature synostosis of the cranial sutures can occur either isolated (non-syndromic) or as part of a Eva-...

BACKGROUND This study was performed to find out whether transcutaneous bilirubinometry could be a valid screening method for hyperbilirubinemia in preterm infants, especially for those who needed mechanical ventilation. METHODS We evaluated 63 preterm Iranian newborns who were managed in the neonatal intensive care unit of Shahidbeheshti University Hospital, Isfahan, Iran from April 2009 to A...

Introduction: The influence of nitric oxide (NO) on blood platelets in premature newborns remains largely unexplained. Material and methods: The expression of the activated GPIIb-IIIa complex and P-selectin were monitored by flow cytometry in whole blood platelets originating from 21 premature, 19 full-term neonates and 27 adults. Platelets were incubated with either freshly generated NO, L-arg...

Background: Positioning of premature newborns significantly affects their health status. However, the most suitable position remains controversial. The current study aimed to compare the effect of supine and prone positions on oxygen saturation and vital signs in premature newborns. Methods: In this crossover clinical trial, a total of 22 new...