The purpose of the present study was to compare the ontogenetic development of the activity of myocardial energy-supplying enzymes in two mammalian species, differing significantly in their level of maturation at birth. The animals were investigated during the late prenatal period and 2, 7, 14, 21, 25, 30, 63, 120 and 730 days after birth in the rat and 2, 21, 84 and 175 days in the guinea-pig....

Supplementation of maternal diet with the essential nutrient, choline, during the second half of pregnancy in rats causes long-lasting improvements in spatial memory in the offspring and protects them from the memory decline characteristic of old age. In contrast, prenatal choline deficiency is associated with poor performance in certain cognitive tasks. The mechanism by which choline influence...

background: fetal alcohol syndrome is associated with numerous problems in the development and function of the brain. learning and memory deficits are among well known effects of prenatal exposure to alcohol. objective: this study aimed to examine the spatial working memory of 60-day old rats who were exposed to alcohol during their fetal life and to find the relation between the possible alcoh...

Prenatal stress in rats results in structural, physiological and behavioral alterations that persist in adulthood. Serotonin (5-HT) is an important neurotransmitter known to be involved in these prenatal stress-induced behavioral alterations. The aim of the study was to investigate the effects of interrupted synthesis of 5-HT and immobilization stress during different gestational period on brai...

People are especially vulnerable to environmental pollutants while in the womb, or prenatal period, and throughout childhood. During these times, environmental chemicals are more likely to have impacts on health and normal growth, and can cause serious health effects later in life. For example, research has shown that when pregnant women are exposed to pesticides, their children may have an inc...

We used in vitro DNA amplification by the polymerase chain reaction and nonradioactive probes for prenatal diagnosis of beta thalassemia in Chinese from the Guangdong province. Exact molecular diagnoses were made in all 20 fetuses studied over a 6-month period. We conclude that this method of prenatal diagnosis for beta thalassemia is a viable approach in many parts of the world where this dise...

Airway problems in an unborn foetus that may cause obstruction can be safely managed using an ex-utero intrapartum technique. Advanced technology now allows many congenital airway problems to be diagnosed in the prenatal period. Careful prenatal planning of an ex-utero intrapartum treatment allows safe airway control while the foetus remains on uteroplacental support. It avoids the need for eme...

This study aims to understand the production of comprehensive care in prenatal care in a Basic Unity of Family Health in Fortaleza. To this end, we conducted semi-structured interviews with a user, whose prenatal care was provided by a Basic Unity of Family Health, as well as systematic observations of her prenatal care appointments. Data analysis, conducted according to Merhy’s analytic flowch...

OBJECTIVES AND METHODS To investigate the impact of prenatal diagnosis on trisomy 21 live births, we collected all prenatal and postnatal trisomy 21 cases (n = 1096) in the eastern half of Switzerland for the years 1980-1996. RESULTS Despite increasing prenatal detection rates of trisomy 21 foetuses (an increase of 169% in the last 5 versus the first 5 years of the study period) and subsequen...

the prevalence of primary infection with t. gondii in pregnant women and risk of congenital infection in their neonates in various parts of tehran are unknown. the prevalence rate of antibodies to t. gondii ranges from 24% in tehran to 62.7% in babol. this study describes the epidemiology of toxoplasma infection in pregnant women in tehran and risk factors of congenital toxoplasmosis in newborn...