▼ Familial forms of primary aldosteronism have been suggested to account for up to 6 % of cases in referral centers. For many years, the genetics of familial hyperaldosteronism remained unknown, with the notable exception of glucocorticoid-remediable aldosteronism, due to unequal crossing over and formation of a chimeric 11β-hydroxylase/ aldosterone synthase gene. Over the past 5 years, mutatio...